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SH3BP4

SH3-domain binding protein 4

May function in transferrin receptor internalization at the plasma membrane through a cargo-specific control of clathrin-mediated endocytosis. Alternatively, may acts as a negative regulator of the amino acid-induced TOR signaling by inhibiting the formation of active Rag GTPase complexes. Preferentially binds inactive Rag GTPase complexes and prevents their interaction with the mTORC1 complex inhibiting its relocalization to lysosomes and its activation. Thereby, may indirectly regulate cell growth, proliferation and autophagy.

Gene Name: SH3-domain binding protein 4
Synonyms: SH3BP4, BOG25, EHB10, EH-binding protein 10, SH3-domain binding protein 4, TTP, SH3 domain-binding protein 4
Target Sequences: NM_014521 NP_055336.1 Q9P0V3

☰ Filters
Antibodies (20)
Proteins (4)
Over-Expression Lysate (2)
Primary (20)
Recombinant (2)
SH3BP4 (24)
Human (19)
Mouse (9)
Rat (8)
Bat (6)
Bovine (6)
Chicken (3)
Chimpanzee (6)
Dog (6)
Gibbon (6)
Guinea pig (3)
Hamster (6)
Horse (6)
Monkey (6)
Orangutan (3)
Rabbit (3)
Zebrafish (4)
IHC (1)
IHC-P (1)
WB (20)
ELISA (9)
IF (1)
IP (1)
Peptide-ELISA (1)
rabbit (20)
Product Group
IHCPlus (1)
IgG (9)
polyclonal pc (20)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (3)
FITC Conjugated (3)
HRP Conjugated (3)
PE Conjugated (1)
Unconjugated (9)
aa402-429 (7)
aa105-154 (4)
aa71-120 (4)
aa132-165 (1)
No (24)
GST, N-terminus (1)
Myc-DDK (Flag) (3)
Human (3)
293T Cells (1)
HEK 293 Cells (2)
Wheat Germ Extract (1)
SH3BP4 Antibody - Anti-SH3BP4 antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Select
SH3BP4 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, IHC-P, WB
Unconjugated
0.05 mg/$460
Select
SH3BP4 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IP, WB
Unconjugated
100 µg/$341
Select
SH3BP4 Rabbit anti-Human Polyclonal (aa402-429) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
Select
SH3BP4 Rabbit anti-Human Polyclonal (aa402-429) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
Select
SH3BP4 Rabbit anti-Human Polyclonal (aa402-429) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
Select
SH3BP4 Rabbit anti-Human Polyclonal (aa402-429) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
Select
SH3BP4 Rabbit anti-Human Polyclonal (aa402-429) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
Select
SH3BP4 Rabbit anti-Human Polyclonal (aa402-429) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
Select
SH3BP4 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
100 µg/$357
SH3BP4 Antibody - Western blot of lysate from ZF4 cell line, using DANRE sh3bp4a antibody diluted at 1:1000. A goat anti-rabbit IgG H&L (HRP) at 1:10000 dilution was used as the secondary antibody. Lysate at 20 ug.
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SH3BP4 Rabbit anti-Zebrafish Polyclonal (aa132-165) Antibody
Zebrafish
Peptide-ELISA, WB
Unconjugated
400 µl/$393
SH3BP4 Antibody - SH3BP4 antibody Western blot of ACHN lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
SH3BP4 Rabbit anti-Human Polyclonal (aa71-120) Antibody
Human
WB
Unconjugated
100 µl/$424
SH3BP4 Antibody - SH3BP4 antibody Western blot of ACHN lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
SH3BP4 Rabbit anti-Human Polyclonal (aa71-120) (HRP) Antibody
Chicken, Zebrafish, Horse, Bat, Bovine, Rabbit, Mouse, Dog, Rat, Hamster, Human, Monkey, Gibbon, Chimpanzee
WB
HRP Conjugated
100 µl/$469
SH3BP4 Antibody - SH3BP4 antibody Western blot of ACHN lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
SH3BP4 Rabbit anti-Human Polyclonal (aa71-120) (Biotin) Antibody
Chicken, Zebrafish, Horse, Bat, Bovine, Rabbit, Mouse, Dog, Rat, Hamster, Human, Monkey, Gibbon, Chimpanzee
WB
Biotin Conjugated
100 µl/$469
SH3BP4 Antibody - SH3BP4 antibody Western blot of ACHN lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
SH3BP4 Rabbit anti-Human Polyclonal (aa71-120) (FITC) Antibody
Chicken, Zebrafish, Horse, Bat, Bovine, Rabbit, Mouse, Dog, Rat, Hamster, Human, Monkey, Gibbon, Chimpanzee
WB
FITC Conjugated
100 µl/$469
SH3BP4 Antibody - SH3BP4 Antibody western blot of 293 cell line lysates (35 ug/lane). The SH3BP4 antibody detected the SH3BP4 protein (arrow).
Select
SH3BP4 Rabbit anti-Human Polyclonal (aa402-429) Antibody
Human
WB
Unconjugated
400 µl/$393
SH3BP4 Antibody - Western blot of Human THP-1. SH3BP4 antibody dilution 1.0 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
SH3BP4 Rabbit anti-Human Polyclonal (aa105-154) Antibody
Human
WB
Unconjugated
100 µl/$424
SH3BP4 Antibody - Western blot of Human THP-1. SH3BP4 antibody dilution 1.0 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
SH3BP4 Rabbit anti-Human Polyclonal (aa105-154) (HRP) Antibody
Mouse, Dog, Guinea pig, Bovine, Rat, Hamster, Horse, Bat, Gibbon, Orangutan, Chimpanzee, Human, Monkey
WB
HRP Conjugated
100 µl/$469
SH3BP4 Antibody - Western blot of Human THP-1. SH3BP4 antibody dilution 1.0 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
SH3BP4 Rabbit anti-Human Polyclonal (aa105-154) (Biotin) Antibody
Mouse, Dog, Guinea pig, Bovine, Rat, Hamster, Horse, Bat, Gibbon, Orangutan, Chimpanzee, Human, Monkey
WB
Biotin Conjugated
100 µl/$469
SH3BP4 Antibody - Western blot of Human THP-1. SH3BP4 antibody dilution 1.0 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
SH3BP4 Rabbit anti-Human Polyclonal (aa105-154) (FITC) Antibody
Mouse, Dog, Guinea pig, Bovine, Rat, Hamster, Horse, Bat, Gibbon, Orangutan, Chimpanzee, Human, Monkey
WB
FITC Conjugated
100 µl/$469
SH3BP4 Antibody - Western blot analysis of extracts of various cell lines, using SH3BP4 antibody at 1:1000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 90s.
Select
SH3BP4 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
SH3BP4 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
SH3BP4 Protein - Purified recombinant protein SH3BP4 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
Select
HEK 293 Cells
Myc-DDK (Flag)
107.3 kDa
20 µg/$1,107
SH3BP4 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
107.3 kDa
20 µg/$150
SH3BP4 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
107.3 kDa
100 µg/$494
Viewing 1-24 of 24 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).