SH2B2 / APS

SH2B adaptor protein 2

Adapter protein for several members of the tyrosine kinase receptor family. Involved in multiple signaling pathways. May be involved in coupling from immunoreceptor to Ras signaling. Acts as a negative regulator of cytokine signaling in collaboration with CBL. Binds to EPOR and suppresses EPO-induced STAT5 activation, possibly through a masking effect on STAT5 docking sites in EPOR. Suppresses PDGF-induced mitogenesis. May induce cytoskeletal reorganization via interaction with VAV3.

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Products

Antibodies (5)

Proteins (4)

Type

Over-Expression Lysate (2)

Primary (5)

Recombinant (2)

Target

SH2B2 / APS (9)

Reactivity

Human (4)

Mouse (5)

Rat (4)

Application

IHC (1)

WB (5)

ELISA (3)

IF (1)

Peptide-ELISA (1)

Host

rabbit (5)

Isotype

IgG (4)

Clonality

polyclonal pc (5)

Format

Unconjugated (5)

Epitope

Internal (2)

N-Terminus (1)

Publications

No (9)

Tag

GST, N-terminus (1)

Myc-DDK (Flag) (3)

Species

Human (3)

Source

293T Cells (1)

HEK 293 Cells (2)

Wheat Germ Extract (1)

Select

SH2B2 / APS Antibody (Internal) LS-C153543

Antibody:

SH2B2 / APS Rabbit anti-Mouse Polyclonal (Internal) Antibody

Reactivity:

Mouse, Rat

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

50 µg/$440; 100 µg/$480

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SH2B2 / APS Antibody LS-C805414

Antibody:

SH2B2 / APS Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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SH2B2 / APS Antibody (Internal) LS-C382075

Antibody:

SH2B2 / APS Rabbit anti-Human Polyclonal (Internal) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

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SH2B2 / APS Antibody LS-C824613

Antibody:

SH2B2 / APS Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$357

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SH2B2 / APS Antibody (N-Terminus) LS-C35051

Antibody:

SH2B2 / APS Rabbit anti-Human Polyclonal (N-Terminus) Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$688

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Human SH2B2 / APS Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G67379

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

72.1 kDa

Price:

20 µg/$1,107

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Human SH2B2 / APS Protein (Recombinant GST, N-terminus) (aa311-410) - LS-G61579

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

Select

Human SH2B2 / APS Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G79703

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

72.1 kDa

Price:

20 µg/$215

Select

SH2B2 / APS Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G129087

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

72.1 kDa

Price:

100 µg/$710

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