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Anti-SH2B2 / APS Antibody (Internal) LS-C153543

Ordering

Wt. Vol. Conc. Price
100 µg 100 µl 1 mg/ml $315
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

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Most Popular SH2B2 / APS Antibodies

Anti-SH2B2 / APS Antibody (N-Terminus) LS-C35051
Rabbit Polyclonal (IgG) to Human SH2B2 / APS
Human, Mouse
Western blot
Unconjugated
Anti-SH2B2 / APS Antibody (aa620-632) LS-C126877
Goat Polyclonal (IgG) to Human SH2B2 / APS
Human, Monkey, Mouse, Rat, Hamster
Western blot
Unconjugated

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal to Mouse SH2B2 / APS
Mouse, Rat
IHC, Western blot, ELISA
Unconjugated

Details

Mouse SH2B2 / APS
Rabbit
Mouse, Rat (tested or 100% immunogen sequence identity)
Polyclonal
Unconjugated
Protein A purified
Unmodified

Applications

  • IHC
  • Western blot
  • ELISA

Specificity and Use

SH2B2 / APS antibody was raised against synthetic peptide derived from internal part of mouse Sh2b2 protein.
Internal
Reacts with 66 kD Sh2b2 protein from mouse and rat. May cross react with human due to partial sequence homology.

Packaging

100 mM Tris-glycine, 2% sucrose
100 µl Distilled water
Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at 4°C. For extended periods store in aliquots at -20°C.
For research use only.

About SH2B2 / APS

NM_020979

SH2B2 Antibody, APS Antibody, SH2B adapter protein 2 Antibody, SH2B adaptor protein 2 Antibody

Adapter protein for several members of the tyrosine kinase receptor family. Involved in multiple signaling pathways. May be involved in coupling from immunoreceptor to Ras signaling. Acts as a negative regulator of cytokine signaling in collaboration with CBL. Binds to EPOR and suppresses EPO-induced STAT5 activation, possibly through a masking effect on STAT5 docking sites in EPOR. Suppresses PDGF-induced mitogenesis. May induce cytoskeletal reorganization via interaction with VAV3.

Requested From: United States
Date Requested: 12/7/2016

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