SET / TAF-I

SET nuclear oncogene

Multitasking protein, involved in apoptosis, transcription, nucleosome assembly and histone chaperoning. Isoform 2 anti-apoptotic activity is mediated by inhibition of the GZMA-activated DNase, NME1. In the course of cytotoxic T-lymphocyte (CTL)-induced apoptosis, GZMA cleaves SET, disrupting its binding to NME1 and releasing NME1 inhibition. Isoform 1 and isoform 2 are potent inhibitors of protein phosphatase 2A. Isoform 1 and isoform 2 inhibit EP300/CREBBP and PCAF-mediated acetylation of histones (HAT) and nucleosomes, most probably by masking the accessibility of lysines of histones to the acetylases. The predominant target for inhibition is histone H4. HAT inhibition leads to silencing of HAT-dependent transcription and prevents active demethylation of DNA. Both isoforms stimulate DNA replication of the adenovirus genome complexed with viral core proteins; however, isoform 2 specific activity is higher.

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Products

Antibodies (38)

Proteins (5)

ELISA Kits (3)

Type

Over-Expression Lysate (2)

Primary (38)

Recombinant (3)

Sandwich (3)

Target

SET / TAF-I (46)

Reactivity

Human (39)

Mouse (14)

Rat (13)

Bovine (8)

Chicken (8)

Chimpanzee (3)

Guinea pig (3)

Hamster (1)

Horse (4)

Monkey (6)

Pig (4)

Rabbit (3)

Xenopus (5)

Zebrafish (5)

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Application

IHC (20)

IHC-P (7)

WB (31)

ELISA (11)

ICC (5)

IF (4)

IP (5)

Peptide-ELISA (3)

Host

rabbit (36)

mouse (1)

goat (1)

Product Group

IHCPlus (3)

Isotype

IgG (32)

IgG1,k (1)

Clonality

monoclonal mc (1)

polyclonal pc (37)

Clone

M1-F5 (1)

Format

96-Well Strip Plate (3)

APC Conjugated (1)

Azide-free (1)

Biotin Conjugated (4)

FITC Conjugated (3)

HRP Conjugated (3)

PE Conjugated (1)

Preservative Free (3)

Unconjugated (26)

Epitope

aa47-75 (7)

aa35-84 (4)

aa125-175 (2)

aa1-45 (1)

aa175-225 (1)

aa2-15 (1)

aa66-81 (1)

Publications

No (46)

Sample Type

Plasma (3)

Serum (3)

Tag

GST (1)

His (1)

Myc-DDK (Flag) (3)

Species

Human (4)

Source

293T Cells (1)

E. coli (1)

HEK 293 Cells (2)

Wheat Germ Extract (1)

Purification

Purified (2)

Select

SET / TAF-I Antibody (clone M1-F5) LS-C198177

Antibody:

SET / TAF-I Mouse anti-Human Monoclonal (M1-F5) Antibody

Reactivity:

Human

Applications:

ELISA, IF, WB

Format:

Unconjugated

Price:

100 µg/$423

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IHC-plus™ SET / TAF-I Antibody (aa2-15) LS-B4032

(4.0) Rating

Antibody:

SET / TAF-I Goat anti-Human Polyclonal (aa2-15) Antibody

Reactivity:

Chicken, Bovine, Human

Applications:

IHC, IHC-P, Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µg/$485

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IHC-plus™ SET / TAF-I Antibody (aa66-81) LS-B2058

(4.0) Rating

Antibody:

SET / TAF-I Rabbit anti-Human Polyclonal (aa66-81) Antibody

Reactivity:

Xenopus, Chicken, Zebrafish, Pig, Horse, Rat, Hamster, Bovine, Mouse, Human, Monkey

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$460

Select

SET / TAF-I Antibody (aa47-75) LS-C330112

Antibody:

SET / TAF-I Rabbit anti-Human Polyclonal (aa47-75) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

200 µl/$734

Select

SET / TAF-I Antibody (aa47-75, Biotin) LS-C269064

Antibody:

SET / TAF-I Rabbit anti-Human Polyclonal (aa47-75) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

Select

SET / TAF-I Antibody (aa47-75, FITC) LS-C269065

Antibody:

SET / TAF-I Rabbit anti-Human Polyclonal (aa47-75) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

FITC Conjugated

Price:

200 µl/$952

Select

SET / TAF-I Antibody (aa47-75, APC) LS-C269063

Antibody:

SET / TAF-I Rabbit anti-Human Polyclonal (aa47-75) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

APC Conjugated

Price:

200 µl/$952

Select

SET / TAF-I Antibody (aa47-75, Azide-free, HRP) LS-C269066

Antibody:

SET / TAF-I Rabbit anti-Human Polyclonal (aa47-75) (Azide-free) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

Select

SET / TAF-I Antibody (aa47-75, PE) LS-C269068

Antibody:

SET / TAF-I Rabbit anti-Human Polyclonal (aa47-75) (PE) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

PE Conjugated

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• APC
• HRP, Azide-free
• PE

• Unconjugated
• Biotin
• FITC
• More...
  • APC
  • HRP, Azide-free
  • PE

Select

IHC-plus™ SET / TAF-I Antibody (aa47-75) LS-B14766

(4.0) Rating

Antibody:

SET / TAF-I Rabbit anti-Human Polyclonal (aa47-75) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, Peptide-ELISA, WB

Format:

Unconjugated

Price:

400 µl/$460

Select

SET / TAF-I Antibody (aa1-45) LS-C185797

Antibody:

SET / TAF-I Rabbit anti-Human Polyclonal (aa1-45) Antibody

Reactivity:

Chicken, Bovine, Human

Applications:

ICC, IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$450

Select

SET / TAF-I Antibody LS-C489255

Antibody:

SET / TAF-I Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ICC, IF, IHC, IHC-P

Format:

Unconjugated

Price:

100 µl/$412

Select

SET / TAF-I Antibody (Preservative Free) LS-C815709

Antibody:

SET / TAF-I Rabbit anti-Human Polyclonal (Preservative Free) Antibody

Reactivity:

Human

Applications:

ICC, IF, IHC-P, IP, WB

Format:

Unconjugated, Preservative Free

Price:

100 µl/$412

Select

SET / TAF-I Antibody LS-C334566

Antibody:

SET / TAF-I Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

Select

SET / TAF-I Antibody LS-C747603

Antibody:

SET / TAF-I Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

Select

SET / TAF-I Antibody LS-C751865

Antibody:

SET / TAF-I Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µg/$341

Select

SET / TAF-I Antibody LS-C809105

Antibody:

SET / TAF-I Rabbit anti-Human Polyclonal Antibody

Reactivity:

Rat, Human

Applications:

IF, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

Select

SET / TAF-I Antibody (aa125-175) LS-C289014

Antibody:

SET / TAF-I Rabbit anti-Human Polyclonal (aa125-175) Antibody

Reactivity:

Mouse, Human

Applications:

IHC, IP, WB

Format:

Unconjugated

Price:

10 µl/$295; 100 µl/$514

Select

SET / TAF-I Antibody (aa175-225) LS-C289017

Antibody:

SET / TAF-I Rabbit anti-Human Polyclonal (aa175-225) Antibody

Reactivity:

Human

Applications:

IHC, IP, WB

Format:

Unconjugated

Price:

10 µl/$295; 100 µl/$514

Select

SET / TAF-I Antibody LS-C179894

Antibody:

SET / TAF-I Rabbit anti-Human Polyclonal Antibody

Reactivity:

Chicken, Bovine, Human, Monkey

Applications:

ICC, IP, WB

Format:

Unconjugated

Price:

100 µg/$407

Select

SET / TAF-I Antibody LS-C179895

Antibody:

SET / TAF-I Rabbit anti-Human Polyclonal Antibody

Reactivity:

Xenopus, Chicken, Zebrafish, Mouse, Rat, Bovine, Human, Monkey

Applications:

ICC, IP, WB

Format:

Unconjugated

Price:

50 µg/$407

Select

SET / TAF-I Antibody LS-C482536

Antibody:

SET / TAF-I Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$286; 100 µl/$321; 200 µl/$386

Select

SET / TAF-I Antibody LS-C341968

Antibody:

SET / TAF-I Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

50 µl/$356; 100 µl/$461

Select

SET / TAF-I Antibody LS-C770553

Antibody:

SET / TAF-I Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

Select

SET / TAF-I Antibody LS-C671129

Antibody:

SET / TAF-I Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

Viewing 1-25 of 46 product results

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