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SERPINH1 / HSP47

serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)

SERPINH1 / HSP47 is a member of the serpin superfamily of serine proteinase inhibitors. The encoded protein is localized to the endoplasmic reticulum and plays a role in collagen biosynthesis as a collagen-specific molecular chaperone. Autoantibodies to the encoded protein have been found in patients with rheumatoid arthritis. Expression of this gene may be a marker for cancer, and nucleotide polymorphisms in this gene may be associated with preterm birth caused by preterm premature rupture of membranes. Alternatively spliced transcript variants have been observed for this gene, and a pseudogene of this gene is located on the short arm of chromosome 9.

Gene Name: serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
Synonyms: SERPINH1, 47 kDa heat shock protein, AsTP3, Colligin, Colligin-1, Collagen-binding protein, Colligin-2, CBP1, HSP47, OI10, Serpin H1, SERPINH2, CBP2, Collagen-binding protein 1, Colligen, gp46, PIG14, PPROM, RA-A47
Target Sequences: NM_001235 NP_001226.2 P50454

Publications (3)

1
Temporal gene expression profiling of the rat knee joint capsule during immobilization-induced joint contractures. Wong K, Sun F, Trudel G, Sebastiani P, Laneuville O. BMC musculoskeletal disorders. 2015 16:125. (ICC; Human, Rat) [Full Text Article] [PubMed:26006773] [PMC:PMC4443538]
2
Functional genomics study of acute heat stress response in the small yellow follicles of layer-type chickens. Cheng CY, Tu WL, Chen CJ, Chan HL, Chen CF, , Chen HH, Tang PC, Lee YP, Chen SE, , Huang SY, ,. Scientific reports. 2018 8:1320. (WB; Human) [Full Text Article] [PubMed:29358656]
3
Proteomic Analysis of Thermal Regulation of Small Yellow Follicles in Broiler-Type Taiwan Country Chickens. Chuen-Yu Cheng, Wei-Lin Tu, Chao-Jung Chen, Hong-Lin Chan, Chih-Feng Chen, Hsin-Hsin Chen, Pin-Chi Tang, Yen-Pai Lee, Shuen-Ei Chen, San-Yuan Huang. The journal of poultry science. 2018 January;55:120-136. [Full Text Article] [PubMed:32055165] [PMC:PMC6756493]

☰ Filters
Antibodies (43)
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SERPINH1 / HSP47 (65)
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SERPINH1 / HSP47 Antibody - Anti-SERPINH1 / HSP47 antibody IHC of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
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SERPINH1 / HSP47 Mouse anti-Rat Monoclonal (M16.10A1) Antibody
Rabbit, Mouse, Guinea pig, Sheep, Rat, Pig, Human
IHC, IHC-P, WB
Unconjugated
50 µg/$525
SERPINH1 / HSP47 Antibody - Anti-SERPINH1 / HSP47 antibody IHC of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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SERPINH1 / HSP47 Mouse anti-Rat Monoclonal (M16.10A1) Antibody
Chicken, Sheep, Bovine, Rabbit, Mouse, Dog, Guinea pig, Rat, Hamster, Pig, Human, Monkey
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$515
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SERPINH1 / HSP47 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, Flo, IF, IHC, WB
Unconjugated
100 µg/$341
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SERPINH1 / HSP47 Rabbit anti-Human Polyclonal (aa406-417) Antibody
Human
WB
Unconjugated
100 µg/$709
SERPINH1 / HSP47 Antibody - SERPINH1 Antibody (RB18953) IHC of formalin-fixed and paraffin-embedded human testis tissue followed by peroxidase-conjugated secondary antibody and DAB staining.
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SERPINH1 / HSP47 Rabbit anti-Human Polyclonal (aa390-418) Antibody
Human
Flo, IHC, IHC-P, WB
Unconjugated
400 µl/$393
SERPINH1 / HSP47 ELISA Kit
Select
Competitive EIA
96-Well Strip Plate
Mouse
1 - 25 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$913
SERPINH1 / HSP47 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
125 - 8000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$764
SERPINH1 / HSP47 ELISA Kit
Select
Sandwich
96-Well Microplate
Rat
1.563 - 100 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
SERPINH1 / HSP47 Antibody - SERPINH1 Antibody (RB18952) IHC of formalin-fixed and paraffin-embedded human testis tissue followed by peroxidase-conjugated secondary antibody and DAB staining.
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SERPINH1 / HSP47 Rabbit anti-Human Polyclonal (aa169-196) Antibody
Human
Flo, IHC, IHC-P, WB
Unconjugated
400 µl/$393
SERPINH1 / HSP47 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
125 - 8000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$783
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SERPINH1 / HSP47 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
SERPINH1 / HSP47 Antibody - Western blot. All lanes: Serpinh1 antibody at 6 ug/ml+ Jurkat whole cell lysate Goat polyclonal to rabbit at 1:10000 dilution. Predicted band size: 47 kDa. Observed band size: 47 kDa.
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SERPINH1 / HSP47 Rabbit anti-Mouse Polyclonal Antibody
Mouse, Human
ELISA, WB
Unconjugated
50 µg/$294; 100 µg/$360
SERPINH1 / HSP47 Antibody - Immunohistochemistry of paraffin-embedded human tonsil using antibody at 1:100 dilution.
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SERPINH1 / HSP47 Rabbit anti-Human Polyclonal (aa139-418) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$294; 100 µl/$360
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SERPINH1 / HSP47 Mouse anti-Human Monoclonal (None) (1C4-1A6) Antibody
ICC, WB
Unconjugated
200 µg/$465
SERPINH1 / HSP47 Antibody - Western blot analysis of HepG2 cell lysates using SERPINH1 antibody. The lane on the left is treated with the antigen-specific peptide.
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SERPINH1 / HSP47 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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Human Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
45.5kD
10 µg/$321; 50 µg/$534; 500 µg/$1,585; 1 mg/$2,157
SERPINH1 / HSP47 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
1.56 - 100 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$818
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E. coli
His-SUMO
60.77 kD
1 mg/$1,679; 100 µg/$500; 20 µg/$364
SERPINH1 / HSP47 Antibody - Hsp47 antibody IHC-paraffin: Rat Intestine Tissue.
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SERPINH1 / HSP47 Rabbit anti-Human Polyclonal (aa247-418) Antibody
Rat, Human
IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
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SERPINH1 / HSP47 Mouse anti-Human Monoclonal (HRP) Antibody
Human
ELISA, IHC, WB
HRP Conjugated
100 µl/$904
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SERPINH1 / HSP47 Mouse anti-Human Monoclonal (Biotin) Antibody
Human
ELISA, IHC, WB
Biotin Conjugated
100 µl/$904
Select
SERPINH1 / HSP47 Mouse anti-Human Monoclonal (FITC) Antibody
Human
ELISA, IHC, WB
FITC Conjugated
100 µl/$904
Select
SERPINH1 / HSP47 Mouse anti-Human Monoclonal (APC) Antibody
Human
ELISA, IHC, WB
APC Conjugated
100 µl/$904
Select
SERPINH1 / HSP47 Mouse anti-Human Monoclonal (PE) Antibody
Human
ELISA, IHC, WB
PE Conjugated
100 µl/$904
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SERPINH1 / HSP47 Mouse anti-Rat Monoclonal (aa222-251) (134CT3.1.1) Antibody
Rat, Human
ELISA, IHC, WB
Unconjugated
200 µl/$734
Viewing 1-25 of 65 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).