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SERPINF1 / PEDF
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
Neurotrophic protein; induces extensive neuronal differentiation in retinoblastoma cells. Potent inhibitor of angiogenesis. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity.
| Gene Name: | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 |
| Synonyms: | SERPINF1, EPC-1, OI12, PEDF, Serpin F1, PIG35, OI6 |
| Target Sequences: | NM_002615 NP_002606.3 P36955 |
Publications (4)
1
Differentiation of human pluripotent stem cells to retinal pigmented epithelium in defined conditions using purified extracellular matrix proteins. Rowland TJ, Blaschke AJ, Buchholz DE, Hikita ST, Johnson LV, Clegg DO. Journal of tissue engineering and regenerative medicine. 2013 August;7:642-653. [Full Text Article]
[PubMed:22514096]
Related Antibodies: LS-B2471.
2
Malignant ascites: a source of therapeutic protein against ovarian cancer?. Ribaux P, Britan A, Thumann G, Delie F, Petignat P, Cohen M. Oncotarget. 2019 October;10:5894-5905. [Full Text Article]
[PubMed:31666922]
[PMC:PMC6800269]
Related Antibodies: LS-C100901.
3
CSF1R blockade induces macrophage ablation and results in mouse choroidal vascular atrophy and RPE disorganization. Xiao Yang, Lian Zhao, Maria M Campos, Mones Abu-Asab, Davide Ortolan, Nathan Hotaling, Kapil Bharti, Wai T Wong. eLife. 2020 Apr;9:e55564. [Full Text Article]
[PubMed:32234210]
[PMC:PMC7156269]
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Neuroscience
SERPINF1 / PEDF Mouse anti-Human Monoclonal (aa196-347) Antibody
Human
ELISA, ICC, IHC, IHC-Fr, IHC-P, WB
Unconjugated
50 µg/$485
SERPINF1 / PEDF Mouse anti-Human Monoclonal (Biotin) Antibody
Human
ELISA, ICC, IHC, WB
Biotin Conjugated
100 µl/$1,054
SERPINF1 / PEDF Mouse anti-Human Monoclonal (APC) Antibody
Human
ELISA, ICC, IHC, WB
APC Conjugated
100 µl/$1,054
SERPINF1 / PEDF Mouse anti-Human Monoclonal (PE) (10F12.2) Antibody
Human
ELISA, ICC, IHC, WB
PE Conjugated
100 µl/$1,054
SERPINF1 / PEDF Rabbit anti-Human Polyclonal (aa9-36) Antibody
Human
Flo, IHC, IHC-P, WB
Unconjugated
400 µl/$393
SERPINF1 / PEDF Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
SERPINF1 / PEDF Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$657
Sandwich
96-Well Strip Plate
Mouse
0.78 - 50 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$768
HEK 293 Cells
6His, N-terminus
46 kDa
200 µl/$283
SERPINF1 / PEDF Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
SERPINF1 / PEDF Rabbit anti-Human Polyclonal (aa279-306) Antibody
Human
Flo, IHC, IHC-P, WB
Unconjugated
400 µl/$393
Sandwich
96-Well Microplate
Rat
3.125 - 200 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
Sandwich CLIA
12 x 8-Well Microstrips
Human
31.25 - 2000 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$728
Sandwich
96-Well Strip Plate
Mouse
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
SERPINF1 / PEDF Rabbit anti-Human Polyclonal Antibody
Mouse, Human
WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
Sandwich
96-Well Microplate
Human
0.16 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
Sandwich
96-Well Strip Plate
Human
3.12 - 200 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$798
HEK 293 Cells
His, C-Terminal
Less than 1.0 EU/µg protein (determined by LAL method).
45.8 kDa
50 µg/$556
SERPINF1 / PEDF Rabbit anti-Rat Polyclonal (Preservative Free) Antibody
Rat
ELISA, IHC-P, IP, WB
Unconjugated, Preservative Free
100 µl/$412
SERPINF1 / PEDF Rabbit anti-Human Polyclonal (Preservative Free) Antibody
Human
ELISA, WB
Unconjugated, Preservative Free
20 µg/$242; 100 µg/$304; 200 µg/$334; 500 µg/$452
SERPINF1 / PEDF Rabbit anti-Human Polyclonal (Preservative Free) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated, Preservative Free
50 µg/$343
SERPINF1 / PEDF Rabbit anti-Human Monoclonal (Preservative Free) (013) Antibody
Human
ELISA
Unconjugated, Preservative Free
100 µl/$412
SERPINF1 / PEDF Rabbit anti-Mouse Polyclonal (aa19-389) (FITC) Antibody
Mouse
WB
FITC Conjugated
100 µl/$345; 200 µl/$402; 500 µl/$594; 1 ml/$737; 2 ml/$976; 5 ml/$1,676
SERPINF1 / PEDF Rabbit anti-Rat Monoclonal (Preservative Free) (061) Antibody
Rat
ELISA
Unconjugated, Preservative Free
100 µl/$412
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