Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
IHC - Paraffin, Western blot, ELISA, Neutralization
Rabbit Polyclonal (IgG) to Human SERPINE1 / PAI-1
Western blot, ELISA
Human SERPINE1 / PAI-1
Human (tested or 100% immunogen sequence identity)
Protein A purified
Western blot (50 - 100 µg/ml)
ELISA (1 - 10 µg/ml)
Specificity and Use
Recombinant Human PAI-1.
Recognizes human PAI-1.
Suitable for use in ELISA and Western Blot. ELISA: 1-10 ug/ml. Western Blot: 50-100 ug/ml. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
0.05 M sodium phosphate, 0.1 M sodium chloride, 1 mM EDTA, pH 6.6
Short term: store at 4°C. Long term: aliquot and store -20°C. Avoid freeze/thaw cycles. Protect from light.
SERPINE1 / PAI-1 is a member of the serine proteinase inhibitor (serpin) superfamily. This member is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), and hence is an inhibitor of fibrinolysis. Defects in this gene are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency), and high concentrations of the gene product are associated with thrombophilia.