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Anti-SERPINE1 / PAI-1 Antibody (Biotin) LS-C187762

Ordering

Wt. Vol. Conc. Price
50 µg 500 µl 0.1 mg/ml $435
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular SERPINE1 / PAI-1 Antibodies

Anti-SERPINE1 / PAI-1 Antibody (clone 3 PAI) LS-C85375
Mouse Monoclonal [clone 3 PAI] (IgG2b) to Human SERPINE1 / PAI-1
Human
ELISA
Unconjugated
Anti-SERPINE1 / PAI-1 Antibody IHC-plus™ LS-B7483
Rabbit Polyclonal (IgG) to Human SERPINE1 / PAI-1
Human
IHC - Paraffin, Western blot, ELISA, Neutralization
Unconjugated
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal (IgG) to Human SERPINE1 / PAI-1
Human
IHC - Paraffin, Western blot, ELISA
Biotin Conjugated

Details

Human SERPINE1 / PAI-1
Rabbit
Human (tested or 100% immunogen sequence identity)
IgG Polyclonal
Biotin
Affinity purified
Unmodified

Applications

  • IHC - Paraffin
  • Western blot (0.1 - 0.2 µg/ml)
  • ELISA (0.25 - 1 µg/ml)

Specificity and Use

SERPINE1 / PAI-1 antibody was raised against recombinant Human PAI-1.
AHP1617 specifically recognizes human PAI-1 (plasminogen activator inhibitor-1), otherwise known as SERPINE1, a 45kD serine protease inhibitor and member of the serpin family, which acts as the primary inhibitor of tissue plasminogen activator (tPA) and urokinase plasminogen activator (uPA), and hence fibrinolysis. Increased levels of PAI-1 are associated with diabetes, cardiovascular disease and an increased occurrence of thrombosis in obesity, and can be induced by obesity related factors including insulin, glucose and VLDL (very-low-density lipoprotein).
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Packaging

PBS
500 µl Sterile PBS
Prior to reconstitution, +4°C. Following reconstitution store at -20°C. Avoid freeze-thaw cycles.
For research use only.

About SERPINE1 / PAI-1

P05121 NM_000602 NP_000593.1

SERPINE1 Antibody, PAI1 Antibody, PLANH1 Antibody, PAI-1 Antibody, Serpin E1 Antibody

SERPINE1 / PAI-1 is a member of the serine proteinase inhibitor (serpin) superfamily. This member is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), and hence is an inhibitor of fibrinolysis. Defects in this gene are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency), and high concentrations of the gene product are associated with thrombophilia.

Immunohistochemistry

Immunohistochemistry
Immunohistochemistry of formalin-fixed human breast invasive ductal carcinoma stained with Rabbit anti-human PAI-1 following heat mediated antigen retrieval using sodium citrate buffer (pH6.0). This image was taken for the unconjugated form of this product. Other forms have not been tested.
 

Requested From: United States
Date Requested: 12/4/2016

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