SERPINA5 / PCI

serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5

Heparin-dependent serine protease inhibitor acting in body fluids and secretions. Inactivates serine proteases by binding irreversibly to their serine activation site. Involved in the regulation of intravascular and extravascular proteolytic activities. Plays hemostatic roles in the blood plasma. Acts as a procoagulant and proinflammatory factor by inhibiting the anticoagulant activated protein C factor as well as the generation of activated protein C factor by the thrombin/thrombomodulin complex. Acts as an anticoagulant factor by inhibiting blood coagulation factors like prothrombin, factor XI, factor Xa, plasma kallikrein and fibrinolytic enzymes such as tissue- and urinary-type plasminogen activators. In seminal plasma, inactivates several serine proteases implicated in the reproductive system. Inhibits the serpin acrosin; indirectly protects component of the male genital tract from being degraded by excessive released acrosin. Inhibits tissue-and urinary-type plasminogen activator, prostate-specific antigen and kallikrein activities; has a control on the sperm motility and fertilization. Inhibits the activated protein C-catalyzed degradation of SEMG1 and SEMG2; regulates the degradation of semenogelin during the process of transfer of spermatozoa from the male reproductive tract into the female tract. In urine, inhibits urinary-type plasminogen activator and kallikrein activities. Inactivates membrane-anchored serine proteases activities such as MPRSS7 and TMPRSS11E. Inhibits urinary-type plasminogen activator-dependent tumor cell invasion and metastasis. May also play a non-inhibitory role in seminal plasma and urine as a hydrophobic hormone carrier by its binding to retinoic acid.

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Antibodies (64)

ELISA Kits (18)

Proteins (8)

Type

Over-Expression Lysate (2)

Primary (64)

Recombinant (6)

Sandwich (15)

Sandwich CLIA (3)

Target

SERPINA5 / PCI (90)

Reactivity

Human (73)

Mouse (9)

Rat (5)

Bovine (3)

Chicken (2)

Chimpanzee (6)

Dog (7)

Drosophila (3)

Gibbon (3)

Guinea pig (3)

Hamster (3)

Horse (3)

Monkey (3)

Orangutan (3)

Pig (6)

Porcine (2)

Rabbit (2)

Sheep (1)

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Application

IHC (15)

IHC-P (10)

WB (55)

Flo (8)

ELISA (18)

IF (12)

Peptide-ELISA (2)

Host

rabbit (42)

mouse (20)

goat (2)

Product Group

IHCPlus (2)

Isotype

IgG (28)

IgG1 (17)

IgG2b (2)

Clonality

monoclonal mc (20)

polyclonal pc (44)

Clone

OTI1A12 (2)

OTI1A9 (2)

OTI1C4 (2)

OTI1E3 (2)

OTI1F8 (2)

OTI2D10 (2)

OTI2D12 (2)

OTI2F2 (2)

OTI2H10 (2)

Format

12 x 8-Well Microstrips (2)

96-Well Microplate (2)

96-Well Strip Plate (14)

APC (1)

APC Conjugated (2)

Azide-free (1)

Biotin Conjugated (5)

Carrier-free (9)

Cy3 Conjugated (1)

Cy7 Conjugated (1)

FITC Conjugated (5)

HRP Conjugated (6)

PE Conjugated (2)

Unconjugated (42)

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Epitope

aa43-406 (8)

aa5-33 (7)

aa269-318 (4)

aa326-375 (4)

230-310 aa, Internal (1)

Internal (1)

Leu291 (1)

aa260-309 (1)

Publications

No (90)

Sample Type

Cell Culture Supernatants (1)

Plasma (9)

Serum (7)

Tissue Homogenates (1)

Urine (1)

Tag

10His, N-terminus (1)

6His, C-terminus (2)

6His, N-terminus (1)

GST (1)

His (1)

Myc-DDK (Flag) (2)

Species

Human (6)

Mouse (1)

Source

293T Cells (1)

Baculovirus (1)

E. coli (2)

HEK 293 Cells (1)

Human Cells (1)

Mammalian Cells (1)

Wheat Germ Extract (1)

Purification

Purified (3)

Low Endotoxin Level

Low endotoxin level (2)

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Human SERPINA5 / PCI (Sandwich ELISA) ELISA Kit - LS-F6447

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

31.25 - 2000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma

Price:

1 Plate/$834

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SERPINA5 / PCI Antibody (clone OTI2D12) LS-C173821

Antibody:

SERPINA5 / PCI Mouse anti-Human Monoclonal (OTI2D12) Antibody

Reactivity:

Human

Applications:

Flo, IF, WB

Format:

Unconjugated

Price:

100 µl/$434

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SERPINA5 / PCI Antibody (clone OTI2D12, Carrier-free) LS-C787004

Antibody:

SERPINA5 / PCI Mouse anti-Human Monoclonal (Carrier-free) (OTI2D12) Antibody

Reactivity:

Human

Applications:

Flo, IF, WB

Format:

Unconjugated, Carrier-free

Price:

100 µg/$511

• Unconjugated
• Unconjugated, Carrier-free

• Unconjugated
• Unconjugated, Carrier-free

Select

SERPINA5 / PCI Antibody LS-C670934

Antibody:

SERPINA5 / PCI Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IF, IHC, WB

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

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Human SERPINA5 / PCI (Sandwich ELISA) ELISA Kit - LS-F22873

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

1.25 - 80 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$651

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Human SERPINA5 / PCI Protein (Recombinant 6His, N-terminus) (aa43-406) - LS-G25283

Source:

E. coli

Tag:

6His, N-terminus

Molecular Weight:

44.7 kDa

Price:

10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119

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SERPINA5 / PCI Antibody (clone OTI2D10) LS-C337649

Antibody:

SERPINA5 / PCI Mouse anti-Human Monoclonal (OTI2D10) Antibody

Reactivity:

Human

Applications:

Flo, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$434

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SERPINA5 / PCI Antibody (clone OTI2D10, Carrier-free) LS-C786947

Antibody:

SERPINA5 / PCI Mouse anti-Human Monoclonal (Carrier-free) (OTI2D10) Antibody

Reactivity:

Human

Applications:

Flo, IF, IHC, WB

Format:

Unconjugated, Carrier-free

Price:

100 µg/$511

• Unconjugated
• Unconjugated, Carrier-free

• Unconjugated
• Unconjugated, Carrier-free

Select

SERPINA5 / PCI Antibody (aa260-309) LS-C120223

Antibody:

SERPINA5 / PCI Rabbit anti-Human Polyclonal (aa260-309) Antibody

Reactivity:

Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

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SERPINA5 / PCI Antibody (aa5-33) LS-C168980

Antibody:

SERPINA5 / PCI Rabbit anti-Human Polyclonal (aa5-33) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

400 µl/$393

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SERPINA5 / PCI Antibody (aa326-375) LS-B12720

Antibody:

SERPINA5 / PCI Rabbit anti-Human Polyclonal (aa326-375) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$485

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SERPINA5 / PCI Antibody (aa326-375, Biotin) LS-C457599

Antibody:

SERPINA5 / PCI Rabbit anti-Human Polyclonal (aa326-375) (Biotin) Antibody

Reactivity:

Pig, Human, Chimpanzee

Applications:

IHC, IHC-P, WB

Format:

Biotin Conjugated

Price:

100 µl/$469

• Unconjugated
• Biotin

• Unconjugated
• Biotin

Select

SERPINA5 / PCI Antibody (clone OTI1A9) LS-C337666

Antibody:

SERPINA5 / PCI Mouse anti-Human Monoclonal (OTI1A9) Antibody

Reactivity:

Human

Applications:

Flo, IF, WB

Format:

Unconjugated

Price:

100 µl/$434

Select

SERPINA5 / PCI Antibody (clone OTI1A9, Carrier-free) LS-C786984

Antibody:

SERPINA5 / PCI Mouse anti-Human Monoclonal (Carrier-free) (OTI1A9) Antibody

Reactivity:

Human

Applications:

Flo, IF, WB

Format:

Unconjugated, Carrier-free

Price:

100 µg/$511

• Unconjugated
• Unconjugated, Carrier-free

• Unconjugated
• Unconjugated, Carrier-free

Select

SERPINA5 / PCI Antibody LS-C752699

Antibody:

SERPINA5 / PCI Mouse anti-Human Monoclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µg/$361

Select

IHC-plus™ SERPINA5 / PCI Antibody LS-B12815

(4.0) Rating

Antibody:

SERPINA5 / PCI Goat anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P

Format:

Unconjugated

Price:

250 µg/$485

Select

SERPINA5 / PCI Antibody LS-C662125

Antibody:

SERPINA5 / PCI Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

10 µg/$318; 100 µg/$470

Select

SERPINA5 / PCI Antibody LS-C752703

Antibody:

SERPINA5 / PCI Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µg/$351

Select

SERPINA5 / PCI Antibody (230-310 aa, Internal) LS-C385341

Antibody:

SERPINA5 / PCI Rabbit anti-Human Polyclonal (230-310 aa, Internal) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

Select

SERPINA5 / PCI Antibody LS-C404390

Antibody:

SERPINA5 / PCI Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

Select

SERPINA5 / PCI Antibody LS-C810232

Antibody:

SERPINA5 / PCI Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IF, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

Select

SERPINA5 / PCI Antibody (Leu291) LS-C177387

Antibody:

SERPINA5 / PCI Rabbit anti-Human Polyclonal (Leu291) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$321; 100 µl/$403

Select

SERPINA5 / PCI Antibody (clone OTI1F8) LS-C173785

Antibody:

SERPINA5 / PCI Mouse anti-Human Monoclonal (OTI1F8) Antibody

Reactivity:

Human

Applications:

IF, WB

Format:

Unconjugated

Price:

100 µl/$434

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SERPINA5 / PCI Antibody (clone OTI2H10) LS-C173790

Antibody:

SERPINA5 / PCI Mouse anti-Human Monoclonal (OTI2H10) Antibody

Reactivity:

Human

Applications:

IF, WB

Format:

Unconjugated

Price:

100 µl/$434

Select

SERPINA5 / PCI Antibody (Internal) LS-C353655

Antibody:

SERPINA5 / PCI Rabbit anti-Human Polyclonal (Internal) Antibody

Reactivity:

Human, Monkey

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$299

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