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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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SERPINA1 / Alpha 1 Antitrypsin Antibody IHC‑plus™ LS‑B9028
Note: This antibody replaces LS-C41720
Alpha 1 Antitrypsin antibody LS-B9028 is an unconjugated mouse monoclonal antibody to human Alpha 1 Antitrypsin (SERPINA1). Validated for ELISA and IHC. Tested on 20 paraffin-embedded human tissues.
Catalog
Size
Price
LS-B9028-250
250 µg (0.5 mg/ml)
Unavailable

Popular SERPINA1 / Alpha 1 Antitrypsin Products

SERPINA1 / Alpha-1-Antitrypsin antibody LS-C31768 was used in IHC to stain formalin-fixed, paraffin-embedded human kidney.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Applications: IHC, IHC - Paraffin, Western blot
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Product Description

Alpha 1 Antitrypsin antibody LS-B9028 is an unconjugated mouse monoclonal antibody to human Alpha 1 Antitrypsin (SERPINA1). Validated for ELISA and IHC. Tested on 20 paraffin-embedded human tissues.
About SERPINA1 / Alpha 1 Antitrypsin
Inhibitor of serine proteases. Its primary target is elastase, but it also has a moderate affinity for plasmin and thrombin. Irreversibly inhibits trypsin, chymotrypsin and plasminogen activator. The aberrant form inhibits insulin-induced NO synthesis in platelets, decreases coagulation time and has proteolytic activity against insulin and plasmin.Short peptide from AAT: reversible chymotrypsin inhibitor. It also inhibits elastase, but not trypsin. P01009 K02212 AAB59495.1

SERPINA1 Antibody, A1A Antibody, A1AT Antibody, AAT Antibody, Alpha 1 Antitrypsin Antibody, Alpha-1 protease inhibitor Antibody, Alpha-1-antiproteinase Antibody, Alpha-1-antitrypsin Antibody, Alpha1AT Antibody, PRO2275 Antibody, Alpha-1-antitrypsin null Antibody, PI1 Antibody, Serpin A1 Antibody


Specifications

Target
Human SERPINA1 / Alpha 1 Antitrypsin
Host
Mouse
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG2a Monoclonal
Conjugations
Unconjugated
Purification
Protein A purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin (10 µg/ml)
  • ELISA
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
Purified human serum alpha-1-antitrypsin.
Specificity
Recognizes human alpha-1 antitrypsin, a serine protease inhibitor synthesized by the liver. Hereditary deficiency of this protein is associated with pulmonary emphysema and with liver disease, due to the loss of inhibition of neutrophil elastase activity. Shows minimal reactivity with other serum proteins including alpha-1-antichymotrypsin.
Presentation
PBS, pH 7.2, 0.09% sodium azide.
Storage
Short term 4°C, long term aliquot and store at -20°C, avoid freeze-thaw cycles. Store undiluted.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Immunohistochemistry

Anti-SERPINA1 / Alpha 1 Antitrypsin antibody IHC staining of human intravascular plasma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-SERPINA1 / Alpha 1 Antitrypsin antibody IHC staining of human intravascular plasma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Immunohistochemistry

Anti-SERPINA1 / Alpha 1 Antitrypsin antibody IHC staining of human intravascular plasma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-SERPINA1 / Alpha 1 Antitrypsin antibody IHC staining of human intravascular plasma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Immunohistochemistry

Anti-SERPINA1 / Alpha 1 Antitrypsin antibody IHC staining of human intravascular plasma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-SERPINA1 / Alpha 1 Antitrypsin antibody IHC staining of human intravascular plasma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Immunohistochemistry

Anti-SERPINA1 / Alpha 1 Antitrypsin antibody IHC staining of human intravascular plasma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-SERPINA1 / Alpha 1 Antitrypsin antibody IHC staining of human intravascular plasma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.


Requested From: 
Date Requested: 6/21/2018

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