Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Human (tested or 100% immunogen sequence identity)
IHC - Paraffin (2 µg/ml)
Western blot (0.5 - 2 µg/ml)
Specificity and Use
SEPT4 / Septin 4 antibody was raised against peptide corresponding to aa 3-14 of human ARTS.
Recognizes human ARTS (Apoptosis Related Protein in TGF-beta Signaling Pathway), a novel mitochondrial septin-like protein. ARTS translocates to the cell nucleus when apoptosis occurs. It enhances apoptosis induced by TGF-beta and other inducers of apoptosis, such as TNF-alpha and Fas ligand.
Western Blot: 0.5-2 ug/ml. In immunoblots, a band of 32 kD is detected.
PBS, pH 7.4, 0.02% sodium azide
+4°C or -20°C, Avoid repeated freezing and thawing.
SEPT4 Antibody, Brain protein H5 Antibody, ARTS Antibody, BRADEION Antibody, CE5B3 Antibody, Cerebral protein 7 Antibody, H5 Antibody, HCDCREL-2 Antibody, Peanut-like 2 (Drosophila) Antibody, PNUTL2 Antibody, SEP4 Antibody, Septin 4 Antibody, Bradeion beta Antibody, CE5B3 beta Antibody, Hucep-7 Antibody, MART Antibody, Peanut-like protein 2 Antibody, Septin-4 Antibody, Septin-M Antibody
SEPT4 / Septin 4 is a member of the septin family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse, and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is highly expressed in brain and heart.