SEPT2 / Septin 2

septin 2

Filament-forming cytoskeletal GTPase. Required for normal organization of the actin cytoskeleton. Plays a role in the biogenesis of polarized columnar-shaped epithelium by maintaining polyglutamylated microtubules, thus facilitating efficient vesicle transport, and by impeding MAP4 binding to tubulin. Required for the progression through mitosis. Forms a scaffold at the midplane of the mitotic splindle required to maintain CENPE localization at kinetochores and consequently chromosome congression. During anaphase, may be required for chromosome segregation and spindle elongation. Plays a role in ciliogenesis and collective cell movements. In cilia, required for the integrity of the diffusion barrier at the base of the primary cilium that prevents diffusion of transmembrane proteins between the cilia and plasma membranes: probably acts by regulating the assembly of the tectonic-like complex (also named B9 complex) by localizing TMEM231 protein. May play a role in the internalization of 2 intracellular microbial pathogens, Listeria monocytogenes and Shigella flexneri.

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Products

Antibodies (38)

Proteins (19)

ELISA Kits (1)

Type

Over-Expression Lysate (10)

Primary (38)

Recombinant (9)

Sandwich (1)

Target

SEPT2 / Septin 2 (58)

Reactivity

Human (39)

Mouse (18)

Rat (14)

Bat (6)

Bovine (3)

Chicken (3)

Chimpanzee (6)

Dog (6)

Gibbon (6)

Guinea pig (3)

Horse (3)

Monkey (3)

Orangutan (6)

Pig (6)

Rabbit (7)

Xenopus (3)

Zebrafish (3)

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Application

IHC (6)

IHC-P (3)

WB (33)

ELISA (16)

IF (1)

IP (2)

Peptide-ELISA (4)

Host

rabbit (36)

mouse (1)

goat (1)

Product Group

IHCPlus (2)

Isotype

IgG (25)

IgG2a,k (1)

Clonality

monoclonal mc (1)

polyclonal pc (37)

Clone

2F8 (1)

Format

96-Well Strip Plate (1)

APC Conjugated (1)

Azide-free (1)

Biotin Conjugated (5)

FITC Conjugated (5)

HRP Conjugated (5)

PE Conjugated (1)

Unconjugated (21)

Epitope

aa280-309 (7)

N-Terminus (5)

C-Terminus (4)

aa287-336 (4)

80-160 aa, Internal (1)

aa103-152 (1)

aa275-325 (1)

aa311-361 (1)

aa37-49 (1)

aa87-136 (1)

Publications

No (58)

Sample Type

Cell Lysates (1)

Plasma (1)

Serum (1)

Tissue Homogenates (1)

Tag

6His-SUMO, N-terminus (1)

GST (2)

His (1)

Myc-DDK (Flag) (15)

Species

Human (14)

Source

293T Cells (5)

E. coli (2)

HEK 293 Cells (10)

Wheat Germ Extract (2)

Purification

Purified (4)

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IHC-plus™ SEPT2 / Septin 2 Antibody (aa37-49) LS-B3607

(4.0) Rating

Antibody:

SEPT2 / Septin 2 Goat anti-Human Polyclonal (aa37-49) Antibody

Reactivity:

Rabbit, Mouse, Rat, Human

Applications:

IHC, IHC-P, Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µg/$485

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IHC-plus™ SEPT2 / Septin 2 Antibody (aa87-136) LS-B14699

(4.0) Rating

Antibody:

SEPT2 / Septin 2 Rabbit anti-Human Polyclonal (aa87-136) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, IHC-P, Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µl/$460

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SEPT2 / Septin 2 Antibody LS-C805371

Antibody:

SEPT2 / Septin 2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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SEPT2 / Septin 2 Antibody LS-C751695

Antibody:

SEPT2 / Septin 2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µg/$341

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SEPT2 / Septin 2 Antibody LS-C770514

Antibody:

SEPT2 / Septin 2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

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SEPT2 / Septin 2 Antibody LS-C667933

Antibody:

SEPT2 / Septin 2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$286; 100 µl/$321

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SEPT2 / Septin 2 Antibody LS-C334302

Antibody:

SEPT2 / Septin 2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

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SEPT2 / Septin 2 Antibody (N-Terminus) LS-C47110

Antibody:

SEPT2 / Septin 2 Rabbit anti-Human Polyclonal (N-Terminus) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

0.1 mg/$379

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SEPT2 / Septin 2 Antibody (80-160 aa, Internal) LS-C386014

Antibody:

SEPT2 / Septin 2 Rabbit anti-Human Polyclonal (80-160 aa, Internal) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

Select

SEPT2 / Septin 2 Antibody (aa280-309) LS-C325006

Antibody:

SEPT2 / Septin 2 Rabbit anti-Human Polyclonal (aa280-309) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

200 µl/$734

Select

SEPT2 / Septin 2 Antibody (aa280-309, Biotin) LS-C269002

Antibody:

SEPT2 / Septin 2 Rabbit anti-Human Polyclonal (aa280-309) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

Select

SEPT2 / Septin 2 Antibody (aa280-309, FITC) LS-C269003

Antibody:

SEPT2 / Septin 2 Rabbit anti-Human Polyclonal (aa280-309) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

FITC Conjugated

Price:

200 µl/$952

Select

SEPT2 / Septin 2 Antibody (aa280-309, APC) LS-C269001

Antibody:

SEPT2 / Septin 2 Rabbit anti-Human Polyclonal (aa280-309) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

APC Conjugated

Price:

200 µl/$952

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SEPT2 / Septin 2 Antibody (aa280-309, Azide-free, HRP) LS-C269004

Antibody:

SEPT2 / Septin 2 Rabbit anti-Human Polyclonal (aa280-309) (Azide-free) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

Select

SEPT2 / Septin 2 Antibody (aa280-309, PE) LS-C269005

Antibody:

SEPT2 / Septin 2 Rabbit anti-Human Polyclonal (aa280-309) (PE) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

PE Conjugated

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• APC
• HRP, Azide-free
• PE

• Unconjugated
• Biotin
• FITC
• More...
  • APC
  • HRP, Azide-free
  • PE

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SEPT2 / Septin 2 Antibody LS-C824566

Antibody:

SEPT2 / Septin 2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$357

Select

SEPT2 / Septin 2 Antibody (aa103-152) LS-C120356

Antibody:

SEPT2 / Septin 2 Rabbit anti-Human Polyclonal (aa103-152) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

Select

SEPT2 / Septin 2 Antibody (aa275-325) LS-C290853

Antibody:

SEPT2 / Septin 2 Rabbit anti-Human Polyclonal (aa275-325) Antibody

Reactivity:

Mouse, Human

Applications:

IP, WB

Format:

Unconjugated

Price:

10 µl/$295; 100 µl/$514

Select

SEPT2 / Septin 2 Antibody (aa311-361) LS-C290855

Antibody:

SEPT2 / Septin 2 Rabbit anti-Human Polyclonal (aa311-361) Antibody

Reactivity:

Mouse, Human

Applications:

IP, WB

Format:

Unconjugated

Price:

10 µl/$295; 100 µl/$514

Select

SEPT2 / Septin 2 Antibody (clone 2F8) LS-C197763

Antibody:

SEPT2 / Septin 2 Mouse anti-Human Monoclonal (2F8) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

Unconjugated

Price:

100 µg/$423

Select

SEPT2 / Septin 2 Antibody LS-C770516

Antibody:

SEPT2 / Septin 2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

Select

SEPT2 / Septin 2 Antibody (N-Terminus) LS-C111940

Antibody:

SEPT2 / Septin 2 Rabbit anti-Human Polyclonal (N-Terminus) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

Select

SEPT2 / Septin 2 Antibody (aa287-336) LS-C102711

Antibody:

SEPT2 / Septin 2 Rabbit anti-Human Polyclonal (aa287-336) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

Select

SEPT2 / Septin 2 Antibody LS-C395516

Antibody:

SEPT2 / Septin 2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

Select

SEPT2 / Septin 2 Antibody (C-Terminus) LS-C345828

Antibody:

SEPT2 / Septin 2 Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

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