SENP6

SUMO1/sentrin specific peptidase 6

Ubiquitin-like molecules (UBLs), such as SUMO1 (UBL1; MIM 601912), are structurally related to ubiquitin (MIM 191339) and can be ligated to target proteins in a similar manner as ubiquitin. However, covalent attachment of UBLs does not result in degradation of the modified proteins. SUMO1 modification is implicated in the targeting of RANGAP1 (MIM 602362) to the nuclear pore complex, as well as in stabilization of I-kappa-B-alpha (NFKBIA; MIM 164008) from degradation by the 26S proteasome. Like ubiquitin, UBLs are synthesized as precursor proteins, with 1 or more amino acids following the C-terminal glycine-glycine residues of the mature UBL protein. Thus, the tail sequences of the UBL precursors need to be removed by UBL-specific proteases, such as SENP6, prior to their conjugation to target proteins (Kim et al., 2000 [PubMed 10799485]). SENPs also display isopeptidase activity for deconjugation of SUMO-conjugated substrates (Lima and Reverter, 2008 [PubMed 18799455]).

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Products

Antibodies (48)

Proteins (3)

Type

Over-Expression Lysate (2)

Primary (48)

Recombinant (1)

Target

SENP6 (51)

Reactivity

Human (47)

Mouse (7)

Rat (7)

Bat (4)

Bovine (7)

Chicken (4)

Chimpanzee (6)

Dog (4)

Gibbon (3)

Hamster (1)

Horse (7)

Monkey (4)

Orangutan (3)

Pig (3)

Rabbit (4)

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Application

IHC (33)

IHC-P (5)

WB (20)

ELISA (31)

ICC (5)

IF (7)

Peptide-ELISA (4)

Host

rabbit (45)

mouse (1)

goat (2)

Product Group

IHCPlus (1)

Isotype

IgG (36)

IgG2a,k (1)

Clonality

monoclonal mc (1)

polyclonal pc (47)

Clone

4B7 (1)

Format

APC Conjugated (4)

Azide-free (4)

Biotin Conjugated (7)

FITC Conjugated (7)

HRP Conjugated (7)

PE Conjugated (4)

Unconjugated (19)

Epitope

N-Terminus (12)

C-Terminus (11)

aa1081-1112 (7)

aa788-837 (4)

1010-1090 aa, C-terminal (1)

Lys1077 (1)

aa1042-1091 (1)

aa2-14 (1)

aa778-790 (1)

Publications

No (51)

Tag

GST, N-terminus (1)

Myc-DDK (Flag) (2)

Species

Human (2)

Source

293T Cells (1)

HEK 293 Cells (1)

Wheat Germ Extract (1)

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IHC-plus™ SENP6 Antibody (aa1081-1112) LS-B13740

(4.0) Rating

Antibody:

SENP6 Rabbit anti-Human Polyclonal (aa1081-1112) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

200 µl/$460

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SENP6 Antibody (C-Terminus) LS-C354490

Antibody:

SENP6 Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$299

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SENP6 Antibody (aa788-837) LS-C151261

Antibody:

SENP6 Rabbit anti-Mouse Polyclonal (aa788-837) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

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SENP6 Antibody (clone 4B7) LS-C133711

Antibody:

SENP6 Mouse anti-Human Monoclonal (4B7) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µg/$423

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SENP6 Antibody (C-Terminus) LS-C325000

Antibody:

SENP6 Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC

Format:

Unconjugated

Price:

200 µl/$734

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SENP6 Antibody (C-Terminus, Biotin) LS-C240567

Antibody:

SENP6 Rabbit anti-Human Polyclonal (C-Terminus) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, ICC, IF, IHC

Format:

Biotin Conjugated

Price:

200 µl/$952

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SENP6 Antibody (C-Terminus, FITC) LS-C240568

Antibody:

SENP6 Rabbit anti-Human Polyclonal (C-Terminus) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, ICC, IF, IHC

Format:

FITC Conjugated

Price:

200 µl/$952

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SENP6 Antibody (C-Terminus, APC) LS-C240566

Antibody:

SENP6 Rabbit anti-Human Polyclonal (C-Terminus) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, ICC, IF, IHC

Format:

APC Conjugated

Price:

200 µl/$952

Select

SENP6 Antibody (C-Terminus, PE) LS-C240573

Antibody:

SENP6 Rabbit anti-Human Polyclonal (C-Terminus) (PE) Antibody

Reactivity:

Human

Applications:

ELISA, ICC, IF, IHC

Format:

PE Conjugated

Price:

200 µl/$952

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SENP6 Antibody (C-Terminus, Azide-free, HRP) LS-C248116

Antibody:

SENP6 Rabbit anti-Human Polyclonal (C-Terminus) (Azide-free) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, ICC, IF, IHC

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• APC
• PE
• HRP, Azide-free

• Unconjugated
• Biotin
• FITC
• More...
  • APC
  • PE
  • HRP, Azide-free

Select

SENP6 Antibody (aa1081-1112) LS-C324999

Antibody:

SENP6 Rabbit anti-Human Polyclonal (aa1081-1112) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

200 µl/$734

Select

SENP6 Antibody (aa1081-1112, Biotin) LS-C240562

Antibody:

SENP6 Rabbit anti-Human Polyclonal (aa1081-1112) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

Select

SENP6 Antibody (aa1081-1112, FITC) LS-C240563

Antibody:

SENP6 Rabbit anti-Human Polyclonal (aa1081-1112) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

FITC Conjugated

Price:

200 µl/$952

Select

SENP6 Antibody (aa1081-1112, APC) LS-C240560

Antibody:

SENP6 Rabbit anti-Human Polyclonal (aa1081-1112) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

APC Conjugated

Price:

200 µl/$952

Select

SENP6 Antibody (aa1081-1112, PE) LS-C240564

Antibody:

SENP6 Rabbit anti-Human Polyclonal (aa1081-1112) (PE) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

PE Conjugated

Price:

200 µl/$952

Select

SENP6 Antibody (aa1081-1112, Azide-free, HRP) LS-C248114

Antibody:

SENP6 Rabbit anti-Human Polyclonal (aa1081-1112) (Azide-free) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• APC
• PE
• HRP, Azide-free

• Unconjugated
• Biotin
• FITC
• More...
  • APC
  • PE
  • HRP, Azide-free

Select

SENP6 Antibody LS-C800396

Antibody:

SENP6 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

Select

SENP6 Antibody (N-Terminus) LS-C328621

Antibody:

SENP6 Rabbit anti-Human Polyclonal (N-Terminus) Antibody

Reactivity:

Human

Applications:

ELISA, IHC

Format:

Unconjugated

Price:

200 µl/$734

Select

SENP6 Antibody (N-Terminus, APC) LS-C245756

Antibody:

SENP6 Rabbit anti-Human Polyclonal (N-Terminus) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, IHC

Format:

APC Conjugated

Price:

200 µl/$952

• Unconjugated
• APC

• Unconjugated
• APC

Select

SENP6 Antibody (N-Terminus) LS-C328622

Antibody:

SENP6 Rabbit anti-Human Polyclonal (N-Terminus) Antibody

Reactivity:

Human

Applications:

ELISA, IHC

Format:

Unconjugated

Price:

200 µl/$734

Select

SENP6 Antibody (1010-1090 aa, C-terminal) LS-C386011

Antibody:

SENP6 Rabbit anti-Human Polyclonal (1010-1090 aa, C-terminal) Antibody

Reactivity:

Human

Applications:

ELISA, IHC

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

Select

SENP6 Antibody LS-C679420

Antibody:

SENP6 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

Select

SENP6 Antibody (aa1042-1091) LS-C118616

Antibody:

SENP6 Rabbit anti-Human Polyclonal (aa1042-1091) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, Peptide-ELISA

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

Select

SENP6 Antibody LS-C826792

Antibody:

SENP6 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC

Format:

Unconjugated

Price:

100 µg/$357

Select

SENP6 Antibody (Lys1077) LS-C176349

Antibody:

SENP6 Rabbit anti-Human Polyclonal (Lys1077) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P

Format:

Unconjugated

Price:

50 µl/$321; 100 µl/$403

Viewing 1-25 of 51 product results

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