Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
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order histories, retained contact details for faster checkout, review submissions, and special promotions.
Rabbit Polyclonal (IgG) to Human SEMA7A / Semaphorin 7A
Human, Mouse
IHC, Western blot, ELISA
Unconjugated
Mouse Monoclonal [clone MEM-150] (IgM) to Human SEMA7A / Semaphorin 7A
Human
Flow Cytometry
FITC Conjugated
Details
Human SEMA7A / Semaphorin 7A
Mouse
Human (tested or 100% immunogen sequence identity)
IgM Monoclonal [MEM-150]
Fluorescein
Ion exchange chromatography
Unmodified
Applications
Flow Cytometry
Specificity and Use
HPB-ALL human T cell line.
Reacts with CD108 (JMH blood group antigen), a 80 kD GPI-anchored glycoprotein expressed on various cell types including erythrocytes, lymphoblasts; at low levels it is present on circulating lymphocytes.
The reagent is designed for Flow Cytometry analysis of human blood cells using 20 ul reagent / 100 ul of whole blood or 106 cells in a suspension. The content of a vial (2 ml) is sufficient for 100 tests. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
Packaging
PBS, 15 mM sodium azide, 0.2% high-grade protease free BSA as a stabilizing agent.
Plays an important role in integrin-mediated signaling and functions both in regulating cell migration and immune responses. Promotes formation of focal adhesion complexes, activation of the protein kinase PTK2/FAK1 and subsequent phosphorylation of MAPK1 and MAPK3. Promotes production of proinflammatory cytokines by monocytes and macrophages. Plays an important role in modulating inflammation and T-cell-mediated immune responses. Promotes axon growth in the embryonic olfactory bulb.