Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal (IgG1) to Human SEMA4D / Semaphorin 4D / CD100
Human SEMA4D / Semaphorin 4D / CD100
Human, Monkey (tested or 100% immunogen sequence identity)
Protein G purified
Specificity and Use
Human PHA activated lymphocytes.
Recognizes human CD100. Species cross-reactivity: Cynomolgus monkey and Rhesus monkey.
Suitable for use in Flow Cytometry. Flow Cytometry: Neat. Use 10 ul of the suggested working dilution to label 1E6 cells in 100ul. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
100 tst deionized water
Long term: Add glycerol (40-50%) -20°C; Short term: +4°C.
Cell surface receptor for PLXN1B and PLXNB2 that plays an important role in cell-cell signaling. Promotes reorganization of the actin cytoskeleton and plays a role in axonal growth cone guidance in the developing central nervous system. Regulates dendrite and axon branching and morphogenesis. Promotes the migration of cerebellar granule cells and of endothelial cells. Plays a role in the immune system; induces B-cells to aggregate and improves their viability (in vitro).