Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal [clone C4D204] (IgG1) to Human SEMA4D / Semaphorin 4D / CD100
IHC - Paraffin
Mouse Monoclonal (IgM) to Human SEMA4D / Semaphorin 4D / CD100
IHC - Frozen, Flow Cytometry
Human SEMA4D / Semaphorin 4D / CD100
Human (tested or 100% immunogen sequence identity)
Protein A purified
IHC - Frozen
Specificity and Use
PHA stimulated human PBL.
Recognizes a CD100 molecule of about 150kD.
Suitable for use in Flow Cytometry and Immunohistochemistry. Immunohistochemistry: Frozen sections. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
Supplied as a liquid in PBS, pH 7.5, 5% Glycerol, 0.2% BSA, 0.04% sodium azide.
+4°C or -20°C, Avoid repeated freezing and thawing.
Cell surface receptor for PLXN1B and PLXNB2 that plays an important role in cell-cell signaling. Promotes reorganization of the actin cytoskeleton and plays a role in axonal growth cone guidance in the developing central nervous system. Regulates dendrite and axon branching and morphogenesis. Promotes the migration of cerebellar granule cells and of endothelial cells. Plays a role in the immune system; induces B-cells to aggregate and improves their viability (in vitro).