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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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SELPLG / PSGL‑1 / CD162 Antibody (aa49‑62) LS‑C38649
Antibody
CD162 antibody LS-C38649 is an unconjugated mouse monoclonal antibody to human CD162 (SELPLG / PSGL-1). Validated for ELISA, Flow, Func, ICC, IHC and WB.
Catalog
Size
Price
LS-C38649-100
100 µg
Unavailable

Popular SELPLG / PSGL-1 / CD162 Products

Anti-SELPLG / CD162 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3879 concentration 10 ug/ml.
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Antibody
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Flow cytometry of SELPLG / PSGL-1 / CD162 antibody This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Human
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Antibody
Species: Mouse, Human, Rat
Applications: IHC, Western blot

Product Description

CD162 antibody LS-C38649 is an unconjugated mouse monoclonal antibody to human CD162 (SELPLG / PSGL-1). Validated for ELISA, Flow, Func, ICC, IHC and WB.
About SELPLG / PSGL-1 / CD162
SELPLG / PSGL-1 / CD162 is a glycoprotein that functions as a high affinity counter-receptor for the cell adhesion molecules P-, E- and L- selectin expressed on myeloid cells and stimulated T lymphocytes. As such, this protein plays a critical role in leukocyte trafficking during inflammation by tethering of leukocytes to activated platelets or endothelia expressing selectins. Q14242 NM_003006 NP_002997.2

SELPLG Antibody, CD162 antigen Antibody, CLA Antibody, CD162 Antibody, PSGL1 Antibody, PSGL-1 Antibody, Selectin P ligand Antibody


Specifications

Target
Human SELPLG / PSGL-1 / CD162
Host
Mouse
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG1,k Monoclonal
Conjugations
Unconjugated
Purification
Protein G purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin
  • ICC
  • Western blot (2 µg/ml)
  • Flow Cytometry (10 µg/ml)
  • ELISA
  • Functional Assay
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
Human P Selectin Glycoprotein Ligand-1 (PSGL 1). Epitope: aa49-62; Overlaps the three potential tyrosine sulfation sites at residues 46, 48 and 51 of the mature PSGL 1, a membrane-distal epitope on PSGL 1.
Epitope
aa49-62
Specificity
Recognizes human PSGL 1. Blocks binding of PSGL 1 to P-selectin and L-selectin. Recognizes a membrane-distal epitope on PSGL 1 and blocks binding of (i) PSGL 1 to immobilized P-selectin, (ii) fluid-phase P-selectin to leukocytes, and (iii) neutrophils to P-selectin under both static and a range of shear stress conditions.
Usage
Suitable for use in Immunohistochemistry, Flow Cytometry, Western Blot, ELISA, Immunocytochemistry and Functional Studies. Immunohistochemistry (Paraffin sections): 2 ug/ml. Flow Cytometry: 10 ug/ml per 1E6 cells. Western Blot: 2 ug/ml. Immunocytochemistry (Cell smears): 2 ug/ml.
Presentation
PBS, 40% glycerol.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: 
Date Requested: 6/18/2018

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