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Anti-SELL / L-Selectin / CD62L Antibody (clone MEL-14) LS-C13940

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Rat Monoclonal [clone MEL-14] (IgG2a) to Mouse SELL / L-Selectin / CD62L
Mouse
IHC - Frozen, Immunoprecipitation, Flow Cytometry
Unconjugated

Details

Mouse SELL / L-Selectin / CD62L
Rat
Mouse (tested or 100% immunogen sequence identity)
IgG2a Monoclonal [MEL-14]
Protein G purified

Applications

IHC - Frozen, Immunoprecipitation, Flow Cytometry (1 µg/ml)

Specificity and Use

SELL / L-Selectin / CD62L antibody was raised against mouse B cell lymphoma, 38C-14.
3H1615 reacts with a 90kD protein involved in the homing of lymphocytes to peripheral lymph nodes (CD62L or L-selectin) L-selectin is expressed on most T and B lymphocytes, neutrophils, monocytes and eosinophils. Pre-incubation of lymphocytes with 3H1615 completely and specifically blocks binding of lymphocytes to high endothelial venules (HEV) in vitro and the migration of lymphocytes to lymph nodes in vivo. We recommends the azide free product for use in functional studies.
Flow Cytometry: 1 ug/ml. Immunohistochemistry (frozen). Immunoprecipitation.

Packaging

0.1% sodium azide.
Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.
For research use only.

About SELL / L-Selectin / CD62L

NM_000655

SELL Antibody, CD62L Antibody, CD62L antigen Antibody, LAM-1 Antibody, LAM1 Antibody, LECAM1 Antibody, LEU8 Antibody, Leukocyte adhesion molecule 1 Antibody, Lyam-1 Antibody, LSEL Antibody, gp90-MEL Antibody, HLHRc Antibody, PLNHR Antibody, L-selectin Antibody, Leu-8 Antibody, Selectin L Antibody, LNHR Antibody, LYAM1 Antibody, Lymph node homing receptor Antibody, Lymphocyte adhesion molecule 1 Antibody, TQ1 Antibody, Pln homing receptor Antibody

SELL / L-Selectin / CD62L is a cell surface adhesion molecule that belongs to a family of adhesion/homing receptors. The encoded protein contains a C-type lectin-like domain, a calcium-binding epidermal growth factor-like domain, and two short complement-like repeats. The gene product is required for binding and subsequent rolling of leucocytes on endothelial cells, facilitating their migration into secondary lymphoid organs and inflammation sites.

Requested From: United States
Date Requested: 9/26/2016

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