Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Rat Monoclonal [clone MEL-14] (IgG2a) to Mouse SELL / L-Selectin / CD62L
Mouse SELL / L-Selectin / CD62L
Mouse (tested or 100% immunogen sequence identity)
IgG2a Monoclonal [MEL-14]
Protein G purified
Flow Cytometry (0.2 µg/10E6 cells)
Specificity and Use
SELL / L-Selectin / CD62L antibody was raised against mouse B cell lymphoma, 38C-14.
Anti-mouse CD62L (L-selectin) monoclonal antibody reacts with a 90 kD protein which is involved with the homing of lymphocytes to peripheral lymph nodes. L-selectin is expressed on most T and B lymphocytes, neutrophils, monocytes, eosinophils.1 Pre-incub.
The applications listed have been tested for the unmodified form of this product. Other forms have not been tested.
SELL / L-Selectin / CD62L is a cell surface adhesion molecule that belongs to a family of adhesion/homing receptors. The encoded protein contains a C-type lectin-like domain, a calcium-binding epidermal growth factor-like domain, and two short complement-like repeats. The gene product is required for binding and subsequent rolling of leucocytes on endothelial cells, facilitating their migration into secondary lymphoid organs and inflammation sites.