Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Rabbit Polyclonal (IgG) to Human SELL / L-Selectin / CD62L
IHC - Paraffin, Western blot, Flow Cytometry
Mouse Monoclonal [clone LAM1-116] (IgG2a,k) to Human SELL / L-Selectin / CD62L
Flow Cytometry, Functional Assay
Human SELL / L-Selectin / CD62L
Human (tested or 100% immunogen sequence identity)
IgG2a,k Monoclonal [LAM1-116]
Specificity and Use
Mouse pre-B cells expressing human L-selectin.
Lectin binding domain of human, mouse, rat and guinea pig CD62L.
Function: Blocks CD62L function and induces expression of beta-1 and beta-2 integrins. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
50 mM sodium phosphate, pH 7.5, 500 mM potassium chloride, 150 mM sodium chloride, 15% Glycerol, 0.2% BSA, 0.04% sodium azide
SELL / L-Selectin / CD62L is a cell surface adhesion molecule that belongs to a family of adhesion/homing receptors. The encoded protein contains a C-type lectin-like domain, a calcium-binding epidermal growth factor-like domain, and two short complement-like repeats. The gene product is required for binding and subsequent rolling of leucocytes on endothelial cells, facilitating their migration into secondary lymphoid organs and inflammation sites.