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Defines endoplasmic reticulum exit sites (ERES) and is required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus. SAR1A-GTP-dependent assembly of SEC16A on the ER membrane forms an organized scaffold defining an ERES. Required for normal transitional endoplasmic reticulum (tER) organization.
Gene Name: | SEC16 homolog A (S. cerevisiae) |
Synonyms: | SEC16A, KIAA0310, SEC16, p250, RP11-413M3.10, SEC16 homolog A, Protein SEC16 homolog A, SEC16L |
Target Sequences: | AB002308 BAA20769.4 O15027 |
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