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Functions as a component of the nuclear pore complex (NPC) and the COPII coat. At the endoplasmic reticulum, SEC13 is involved in the biogenesis of COPII-coated vesicles. As a component of the GATOR2 complex, inhibits GATOR1 complex, an inhibitor of the amino acid-sensing branch of the TORC1 pathway.
Gene Name: | SEC13 homolog (S. cerevisiae) |
Synonyms: | SEC13, D3S1231E, Protein SEC13 homolog, SEC13-like 1 isoform, SEC13R, SEC13 (S. cerevisiae)-like 1, SEC13 homolog (S. cerevisiae), SEC13-like 1 (S. cerevisiae), SEC13-like protein 1, SEC13-related protein, SEC13L1, Npp-20 |
Target Sequences: | NM_030673 NP_899195.1 P55735 |
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