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Anti-SDF1 / CXCL12 Antibody IHC-plus™ LS-B2437

Note: This antibody replaces LS-C17941

Ordering

Wt. Vol. Conc. Price
50 µg - 1 mg/ml $450
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular SDF1 / CXCL12 Antibodies

Anti-SDF1 / CXCL12 Antibody (C-Terminus) IHC-plus™ LS-B943
Rabbit Polyclonal to Human SDF1 / CXCL12
Human, Monkey, Mouse, Bat, Dog, Guinea pig, Horse, Pig, Chicken, Xenopus
IHC - Paraffin, Western blot
Unconjugated
Immunohistochemistry Image
Anti-SDF1 / CXCL12 Antibody IHC-plus™ LS-B7489
Rabbit Polyclonal (IgG) to Human SDF1 / CXCL12
Human
IHC - Paraffin, Western blot, ELISA, Neutralization
Unconjugated
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal (IgG) to Rat SDF1 / CXCL12
Rat, Human, Mouse
IHC - Paraffin, Western blot, Immunoprecipitation
Unconjugated

Details

Rat SDF1 / CXCL12
Rabbit
Rat, Human, Mouse (tested or 100% immunogen sequence identity)
IgG Polyclonal
Unconjugated
Protein A purified
Unmodified

Applications

  • IHC - Paraffin (5 µg/ml)
  • Western blot (1:1000)
  • Immunoprecipitation (1:300 - 1:500)

Specificity and Use

SDF1 / CXCL12 antibody was raised against e. coli-expressed mouse SDF-1b.
Recognizes rat SDF-1b. Species cross-reactivity: mouse.
Immunohistochemistry: LS-B2437 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B2437 was determined to be 5 ug/ml.

Packaging

0.05% sodium azide
+4°C or -20°C, Avoid repeated freezing and thawing.
For research use only.

About SDF1 / CXCL12

P48061 NM_000609 NP_000600.1

CXCL12 Antibody, C-X-C motif chemokine 12 Antibody, HIRH Antibody, IRH Antibody, SDF-1 Antibody, SDF-1b Antibody, SDF1A Antibody, SDF1B Antibody, TPAR1 Antibody, TLSF-a Antibody, TLSF-b Antibody, SDF-1a Antibody, SDF1 Antibody, Sdf1alpha Antibody, Stromal cell-derived factor 1 Antibody, TLSF Antibody, HSDF-1 Antibody, PBSF Antibody, SCYB12 Antibody

Chemoattractant active on T-lymphocytes, monocytes, but not neutrophils. Activates the C-X-C chemokine receptor CXCR4 to induce a rapid and transient rise in the level of intracellular calcium ions and chemotaxis. Also binds to atypical chemokine receptor ACKR3, which activates the beta-arrestin pathway and acts as a scavenger receptor for SDF-1. SDF-1-beta(3-72) and SDF-1-alpha(3-67) show a reduced chemotactic activity.

Immunohistochemistry

Immunohistochemistry
Anti-CXCL12 antibody IHC of human thymus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2437 concentration 5 ug/ml.
 

Requested From: United States
Date Requested: 12/10/2016

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