Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal [clone 2C12] (IgG1,k) to Human SDCBP / Syntenin
IHC - Paraffin, Immunofluorescence, Western blot, Immunoprecipitation, ELISA
Human SDCBP / Syntenin
Human (tested or 100% immunogen sequence identity)
IgG1,k Monoclonal [2C12]
Protein A purified
IHC - Paraffin (5 µg/ml)
Immunofluorescence (35 µg/ml)
Western blot (1:500 - 1:1000)
Specificity and Use
SDCBP / Syntenin antibody was raised against sDCBP (NP_005616, 1 a.a. ~ 101 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Immunohistochemistry: Formalin-fixed paraffin-embedded sections. Sandwich ELISA: Recombinant protein. Western Blot using transfected cell lysates, cell line lysates and the recombinant protein used as the immunogen.
PBS, pH 7.4.
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
SDCBP / Syntenin was initially identified as a molecule linking syndecan-mediated signaling to the cytoskeleton. The syntenin protein contains tandemly repeated PDZ domains that bind the cytoplasmic, C-terminal domains of a variety of transmembrane proteins. This protein may also affect cytoskeletal-membrane organization, cell adhesion, protein trafficking, and the activation of transcription factors.