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SDC1 / Syndecan 1 / CD138
syndecan 1
SDC1 / Syndecan 1 / CD138 is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-1 expression has been detected in several different tumor types. While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same protein.
| Gene Name: | syndecan 1 |
| Synonyms: | SDC1, CD138 antigen, SDC, SYND1, Syndecan, Syndecan 1, Syndecan-1, CD138, Syndecan proteoglycan 1 |
| Target Sequences: | NM_002997 NP_002988.3 P18827 |
Publications (3)
1
Increased CXCR3 Expression of Infiltrating Plasma Cells in Hunner Type Interstitial Cystitis. Akiyama Y, Morikawa T, Maeda D, Shintani Y, Niimi A, Nomiya A, Nakayama A, Igawa Y, Fukayama M, Homma Y. Scientific reports. 2016 6:28652. (IHC-P; Human)
[Full Text Article]
[PubMed:27339056]
[PMC:PMC4919639]
2
Halting the vicious cycle within the multiple myeloma ecosystem: blocking JAM-A on bone marrow endothelial cells restores the angiogenic homeostasis and suppresses tumor progression. Antonio G Solimando, Matteo C Da Vià, Patrizia Leone, Paola Borrelli, Giorgio A Croci, Paula Tabares, Andreas Brandl, Giuseppe Di Lernia, Francesco P Bianchi, Silvio Tafuri, Torsten Steinbrunn, Alessandra Balduini, Assunta Melaccio, Simona De Summa, Antonella Argentiero, Hilka Rauert-Wunderlich, Maria A Frassanito, Paolo Ditonno, Erik Henke, Wolfram Klapper, Roberto Ria, Carolina Terragna, Leo Rasche, Andreas Rosenwald, Martin K Kortüm, Michele Cavo, Domenico Ribatti, Vito Racanelli, Hermann Ein. Haematologica. 2020 April; [Full Text Article]
[PubMed:32354870]
[PMC:PMC8252928]
Related Antibodies: LS-B9360.
3
Acetyl-CoA Synthetase 2: A Critical Linkage in Obesity-Induced Tumorigenesis in Myeloma. Zongwei Li, Huan Liu, Jin He, Zhiqiang Wang, Zheng Yin, Gichun You, Zhiming Wang, Richard E Davis, Pei Lin, P Leif Bergsagel, Elisabet E Manasanch, Stephen T C Wong, Nestor F Esnaola, Jenny C Chang, Robert Z Orlowski, Qing Yi, Jing Yang. The Breast : official journal of the European Society of Mastology. 2021 January;33:78-93e7. [Full Text Article]
[PubMed:33406405]
[PMC:PMC7799390]
Related Antibodies: LS-B9360.
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SDC1 / Syndecan 1 / CD138
(155)
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Cancer Pathology
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SDC1 / Syndecan 1 / CD138 Mouse anti-Human Monoclonal (B-A38) Antibody
Human
Flo, IF, IHC, IHC-Fr, IHC-P, WB
Unconjugated
0.05 mg/$460
SDC1 / Syndecan 1 / CD138 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IHC, IHC-P, WB
Unconjugated
50 µl/$485
SDC1 / Syndecan 1 / CD138 Mouse anti-Human Monoclonal (aa28-171) (1A3H4) Antibody
Human
ELISA, Flo, IF, IHC, WB
Unconjugated
0.1 mg/$447; 100 µl/$459
Sandwich
96-Well Strip Plate
Pig
1.56 - 100 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$929
Sandwich
96-Well Strip Plate
Porcine
0.781 - 50 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$768
Sandwich
96-Well Strip Plate
Rat
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum, Tissue Homogenates
1 Plate/$783
Yeast
His
26.5 kD
100 µg/$499; 20 µg/$364; 1 mg/$1,683
Sandwich
96-Well Strip Plate
Mouse
1.56 - 100 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$818
Sandwich
96-Well Microplate
Human
156 - 10000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Serum
1 Plate/$795
Sandwich
96-Well Strip Plate
Human
1.56 - 100 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$798
Sandwich
96-Well Strip Plate
Rat
1.56 - 100 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$856
Competitive EIA
96-Well Strip Plate
Dog
0.5 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum, Tissue Homogenates
1 Plate/$913
SDC1 / Syndecan 1 / CD138 Mouse anti-Human Monoclonal (aa210-238) Antibody
Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
0.05 ml/$460
SDC1 / Syndecan 1 / CD138 Mouse anti-Human Monoclonal Antibody
Human
ELISA, Flo, IHC, IHC-Fr, IHC-P
Unconjugated
50 µg/$485
Sandwich
96-Well Strip Plate
Rat
250 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$913
SDC1 / Syndecan 1 / CD138 Mouse anti-Human Monoclonal (MI15) Antibody
Rat, Non-Human Primates, Human
Flo, IHC-P, IP, WB
Unconjugated
0.1 mg/$316
Cancer Pathology
Cancer
SDC1 / Syndecan 1 / CD138 Mouse anti-Human Monoclonal (Concentrated) Antibody
Human
ELISA, IHC-P
Unconjugated, Concentrated
0.05 ml/$460
SDC1 / Syndecan 1 / CD138 Rabbit anti-Human Polyclonal (Internal) Antibody
Mouse, Rat, Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$485
Human Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
24.65kD
10 µg/$321; 50 µg/$442; 500 µg/$1,585; 1 mg/$2,157
Human Cells
Fc, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
51 kDa
10 µg/$288; 50 µg/$436
E. coli
His
100 µg/$361; 500 µg/$739; 20 µg/$261
SDC1 / Syndecan 1 / CD138 Rat anti-Human Monoclonal (aa18-251) Antibody
Human
ELISA, Flo, IHC
Unconjugated
100 µg/$962
SDC1 / Syndecan 1 / CD138 Rabbit anti-Human Polyclonal (aa83-132) Antibody
Rat, Human
Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
SDC1 / Syndecan 1 / CD138 Rabbit anti-Human Monoclonal (PE) (017) Antibody
Human
Flo
PE Conjugated
25 Tests/$263; 100 Tests/$376
SDC1 / Syndecan 1 / CD138 Rabbit anti-Human Polyclonal (aa23-253) (FITC) Antibody
Human
WB
FITC Conjugated
100 µl/$341; 200 µl/$397; 500 µl/$583; 1 ml/$715; 2 ml/$953; 5 ml/$1,628
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