Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Rabbit Monoclonal [clone SP152] (IgG) to Human SDC1 / Syndecan 1 / CD138
IHC - Paraffin
Mouse Monoclonal (IgG1) to Human SDC1 / Syndecan 1 / CD138
IHC - Paraffin, IHC - Frozen, Flow Cytometry
Human SDC1 / Syndecan 1 / CD138
Human (tested or 100% immunogen sequence identity)
Protein G purified
IHC - Paraffin (1:100)
IHC - Frozen (1:100 - 1:500)
Specificity and Use
U266 cell line.
Recognizes human Syndecan-1 (CD138).
Suitable for use in Flow Cytometry and Immunohistochemistry (frozen and paraffin). Flow Cytometry: Neat; 10 ul labels 10^6 cells in 100ul. Immunohistochemistry (frozen): 1:100-1:500. Immunohistochemistry (paraffin): 1:100.
PBS, 1% BSA, 0.09% sodium azide
May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile 40-50% glycerol, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C.
SDC1 / Syndecan 1 / CD138 is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins.