SCUBE3

signal peptide, CUB domain, EGF-like 3

SCUBE3 is a member of the signal peptide, complement subcomponents C1r/C1s, Uegf, bone morphogenetic protein-1 and epidermal growth factor-like domain containing protein family. Overexpression of this gene in human embryonic kidney cells results in secretion of a glycosylated form of the protein that forms oligomers and tethers to the cell surface. This gene is upregulated in lung cancer tumor tissue compared to healthy tissue and is associated with loss of the epithelial marker E-cadherin and with increased expression of vimentin, a mesenchymal marker. In addition, the protein encoded by this gene is a transforming growth factor beta receptor ligand, and when secreted by cancer cells, it can be cleaved in vitro to release the N-terminal epidermal growth factor-like repeat domain and the C-terminal complement subcomponents C1r/C1s domain. Both the full length protein and C-terminal fragment can bind to the transforming growth factor beta type II receptor to promote the epithelial-mesenchymal transition and tumor angiogenesis. Alternative splicing results in multiple transcript variants.

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Products

Antibodies (21)

Proteins (5)

ELISA Kits (2)

Type

Over-Expression Lysate (2)

Primary (21)

Recombinant (3)

Sandwich (2)

Target

SCUBE3 (28)

Reactivity

Human (23)

Mouse (11)

Rat (3)

Bat (3)

Bovine (3)

Chicken (3)

Chimpanzee (3)

Dog (3)

Gibbon (3)

Guinea pig (3)

Horse (3)

Monkey (3)

Pig (3)

Rabbit (3)

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Application

IHC (2)

IHC-P (1)

WB (21)

ELISA (8)

IF (1)

Host

rabbit (21)

Product Group

IHCPlus (1)

Isotype

IgG (8)

Clonality

polyclonal pc (21)

Format

96-Well Strip Plate (2)

APC (1)

APC Conjugated (2)

Azide-free (1)

Biotin Conjugated (3)

Cy3 Conjugated (1)

Cy7 Conjugated (1)

FITC Conjugated (3)

HRP Conjugated (3)

PE Conjugated (2)

Unconjugated (6)

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Epitope

aa807-993 (8)

aa480-509 (7)

aa159-208 (4)

Publications

No (28)

Sample Type

Plasma (2)

Serum (2)

Tissue Homogenates (1)

Tag

GST, N-terminus (2)

His-T7 (1)

Myc-DDK (Flag) (2)

Species

Human (4)

Source

293T Cells (1)

E. coli (1)

HEK 293 Cells (1)

Wheat Germ Extract (2)

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IHC-plus™ SCUBE3 Antibody LS-B8856

(4.0) Rating

Antibody:

SCUBE3 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

0.05 mg/$545

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SCUBE3 Antibody LS-C754328

Antibody:

SCUBE3 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µg/$341

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SCUBE3 Antibody (aa480-509) LS-C324948

Antibody:

SCUBE3 Rabbit anti-Human Polyclonal (aa480-509) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

200 µl/$734

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SCUBE3 Antibody (aa480-509, Biotin) LS-C240466

Antibody:

SCUBE3 Rabbit anti-Human Polyclonal (aa480-509) (Biotin) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

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SCUBE3 Antibody (aa480-509, FITC) LS-C240468

Antibody:

SCUBE3 Rabbit anti-Human Polyclonal (aa480-509) (FITC) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

FITC Conjugated

Price:

200 µl/$952

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SCUBE3 Antibody (aa480-509, Azide-free, HRP) LS-C248095

Antibody:

SCUBE3 Rabbit anti-Human Polyclonal (aa480-509) (Azide-free) (HRP) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

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SCUBE3 Antibody (aa480-509, APC) LS-C240467

Antibody:

SCUBE3 Rabbit anti-Human Polyclonal (aa480-509) (APC) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

APC Conjugated

Price:

200 µl/$952

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SCUBE3 Antibody (aa480-509, PE) LS-C240471

Antibody:

SCUBE3 Rabbit anti-Human Polyclonal (aa480-509) (PE) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

PE Conjugated

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• HRP, Azide-free
• APC
• PE

• Unconjugated
• Biotin
• FITC
• More...
  • HRP, Azide-free
  • APC
  • PE

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SCUBE3 Antibody (aa159-208) LS-C152186

Antibody:

SCUBE3 Rabbit anti-Human Polyclonal (aa159-208) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

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SCUBE3 Antibody (aa159-208, HRP) LS-C474093

Antibody:

SCUBE3 Rabbit anti-Human Polyclonal (aa159-208) (HRP) Antibody

Reactivity:

Chicken, Bovine, Rabbit, Mouse, Dog, Guinea pig, Pig, Horse, Bat, Rat, Chimpanzee, Gibbon, Human, Monkey

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$469

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SCUBE3 Antibody (aa159-208, Biotin) LS-C474091

Antibody:

SCUBE3 Rabbit anti-Human Polyclonal (aa159-208) (Biotin) Antibody

Reactivity:

Chicken, Bovine, Rabbit, Mouse, Dog, Guinea pig, Pig, Horse, Bat, Rat, Chimpanzee, Gibbon, Human, Monkey

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$469

Select

SCUBE3 Antibody (aa159-208, FITC) LS-C474092

Antibody:

SCUBE3 Rabbit anti-Human Polyclonal (aa159-208) (FITC) Antibody

Reactivity:

Chicken, Bovine, Rabbit, Mouse, Dog, Guinea pig, Pig, Horse, Bat, Rat, Chimpanzee, Gibbon, Human, Monkey

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

SCUBE3 Antibody (aa807-993) LS-C375043

Antibody:

SCUBE3 Rabbit anti-Human Polyclonal (aa807-993) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$318; 200 µl/$364; 500 µl/$518; 1 ml/$595; 2 ml/$822; 5 ml/$1,345

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SCUBE3 Antibody (aa807-993, HRP) LS-C714792

Antibody:

SCUBE3 Rabbit anti-Human Polyclonal (aa807-993) (HRP) Antibody

Reactivity:

Human

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$351; 200 µl/$410; 500 µl/$615; 1 ml/$769; 2 ml/$1,006; 5 ml/$1,748

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SCUBE3 Antibody (aa807-993, Biotin) LS-C689639

Antibody:

SCUBE3 Rabbit anti-Human Polyclonal (aa807-993) (Biotin) Antibody

Reactivity:

Human

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$329; 200 µl/$379; 500 µl/$549; 1 ml/$651; 2 ml/$886; 5 ml/$1,479

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SCUBE3 Antibody (aa807-993, FITC) LS-C696776

Antibody:

SCUBE3 Rabbit anti-Human Polyclonal (aa807-993) (FITC) Antibody

Reactivity:

Human

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$361; 200 µl/$426; 500 µl/$663; 1 ml/$822; 2 ml/$1,063; 5 ml/$1,883

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SCUBE3 Antibody (aa807-993, APC, Cy7) LS-C737701

Antibody:

SCUBE3 Rabbit anti-Human Polyclonal (aa807-993) (APC, Cy7) Antibody

Reactivity:

Human

Applications:

WB

Format:

APC, Cy7 Conjugated

Price:

100 µl/$533; 200 µl/$709; 500 µl/$1,229; 1 ml/$1,537; 2 ml/$2,151; 5 ml/$4,033

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SCUBE3 Antibody (aa807-993, PE) LS-C728868

Antibody:

SCUBE3 Rabbit anti-Human Polyclonal (aa807-993) (PE) Antibody

Reactivity:

Human

Applications:

WB

Format:

PE Conjugated

Price:

100 µl/$426; 200 µl/$518; 500 µl/$913; 1 ml/$1,080; 2 ml/$1,435; 5 ml/$2,689

Select

SCUBE3 Antibody (aa807-993, APC) LS-C719890

Antibody:

SCUBE3 Rabbit anti-Human Polyclonal (aa807-993) (APC) Antibody

Reactivity:

Human

Applications:

WB

Format:

APC Conjugated

Price:

100 µl/$426; 200 µl/$518; 500 µl/$913; 1 ml/$1,080; 2 ml/$1,435; 5 ml/$2,689

Select

SCUBE3 Antibody (aa807-993, Cy3) LS-C705779

Antibody:

SCUBE3 Rabbit anti-Human Polyclonal (aa807-993) (Cy3) Antibody

Reactivity:

Human

Applications:

WB

Format:

Cy3 Conjugated

Price:

100 µl/$426; 200 µl/$518; 500 µl/$913; 1 ml/$1,080; 2 ml/$1,435; 5 ml/$2,689

• Unconjugated
• HRP
• Biotin
• FITC
• APC, Cy7
• PE
• APC
• More...
  • Cy3

• Unconjugated
• HRP
• Biotin
• More...
  • FITC
  • APC, Cy7
  • PE
  • APC
  • Cy3

Select

SCUBE3 Antibody (aa480-509) LS-C158929

Antibody:

SCUBE3 Rabbit anti-Human Polyclonal (aa480-509) Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

Unconjugated

Price:

400 µl/$393

Select

Human SCUBE3 Protein (Recombinant GST, N-terminus) (aa401-499) - LS-G63831

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

Select

Human SCUBE3 Protein (Recombinant GST, N-terminus) (aa29-147) - LS-G63835

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human SCUBE3 (Sandwich ELISA) ELISA Kit - LS-F56005

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

Select

Human SCUBE3 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G92648

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

109.1 kDa

Price:

20 µg/$150

Viewing 1-25 of 28 product results

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