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SCN9A / Nav1.7 Antibody (aa1751‑1946, clone S68‑6) LS‑C109013
Nav1.7 antibody LS-C109013 is an unconjugated mouse monoclonal antibody to Nav1.7 (SCN9A) from human, mouse and rat. Validated for ICC, IHC, IP and WB.
Catalog
Size
Price
LS-C109013-100
100 µg
Unavailable

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Product Description

Nav1.7 antibody LS-C109013 is an unconjugated mouse monoclonal antibody to Nav1.7 (SCN9A) from human, mouse and rat. Validated for ICC, IHC, IP and WB.
About SCN9A / Nav1.7
Scn9a encodes the alpha subunit of the type IX voltage-gated sodium channel. These channels, composed of one alpha and one or two beta subunits, mediate changes in cell permeability to sodium ions that are essential for the generation of action potentials. The alpha subunit alone can generate a functional channel in vitro >, but it's kinetic properties are modulated by beta subunits. The type IX channel is tetrodotoxin sensitive and is believed to function in hyperexcitability induced pain. Q15858 NM_002977 NP_002968.1

SCN9A Antibody, ETHA Antibody, GEFSP7 Antibody, Nav1.7 Antibody, HNE-Na Antibody, Peripheral sodium channel 1 Antibody, PN1 Antibody, SFNP Antibody, Sodium channel 25 Antibody, Neuroendocrine sodium channel Antibody, FEB3B Antibody, NE-NA Antibody, NENA Antibody


Specifications

Target
Human SCN9A / Nav1.7
Host
Mouse
Reactivity
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
Clonality
IgG1 Monoclonal [S68-6]
Conjugations
Unconjugated. Also available conjugated with Atto 390, Atto 488, Atto 565, Atto 594, Atto 655, Atto 633, Atto 700, Atto 680, APC, AP, Biotin, FITC, PE, Atto 594, PerCP, RPE, SA.
Purification
Protein G purified from tissue culture supernatant
Modifications
Unmodified
Applications
  • IHC
  • ICC (0.1 - 1 µg/ml)
  • Western blot (1 - 10 µg/ml)
  • Immunoprecipitation (1 - 10 µg/ml)
  • (applications tested for the base form of this product only)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
SCN9A / Nav1.7 antibody was raised against fusion protein amino acids 1751-1946 (C-terminus) of human Nav1.7, accession number Q15858.
Epitope
aa1751-1946
Specificity
Detects ~230 kD protein. No cross reactivity against other Nav channels.
Usage
Western Blot: Use the lysate in SDS buffer but without boiling, incubating for 20 mins at 37°C instead.
Presentation
PBS, pH 7.4, 50% glycerol, 0.09% sodium azide
Storage
Store at -20°C.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Immunohistochemistry

IHC analysis of Nav1.7 in mouse brain tissue using a dilution of SCN9A / Nav1.7 antibody.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
IHC analysis of Nav1.7 in mouse brain tissue using a dilution of SCN9A / Nav1.7 antibody. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Immunofluorescence

Nav1.7 (S68-6), Human hippocampus.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Nav1.7 (S68-6), Human hippocampus. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Immunofluorescence

Nav1.7 (S68-6), Mouse back skin.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Nav1.7 (S68-6), Mouse back skin. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

Nav1.7 (S68-6), T-CHO.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Nav1.7 (S68-6), T-CHO. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Immunohistochemistry

IHC analysis of Nav1.7 in mouse brain tissue using a dilution of SCN9A / Nav1.7 antibody.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
IHC analysis of Nav1.7 in mouse brain tissue using a dilution of SCN9A / Nav1.7 antibody. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Immunofluorescence

Nav1.7 (S68-6), Human hippocampus.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Nav1.7 (S68-6), Human hippocampus. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Immunofluorescence

Nav1.7 (S68-6), Mouse back skin.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Nav1.7 (S68-6), Mouse back skin. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

Nav1.7 (S68-6), T-CHO.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Nav1.7 (S68-6), T-CHO. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Immunohistochemistry

IHC analysis of Nav1.7 in mouse brain tissue using a dilution of SCN9A / Nav1.7 antibody.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
IHC analysis of Nav1.7 in mouse brain tissue using a dilution of SCN9A / Nav1.7 antibody. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Immunofluorescence

Nav1.7 (S68-6), Human hippocampus.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Nav1.7 (S68-6), Human hippocampus. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Immunofluorescence

Nav1.7 (S68-6), Mouse back skin.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Nav1.7 (S68-6), Mouse back skin. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

Nav1.7 (S68-6), T-CHO.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Nav1.7 (S68-6), T-CHO. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Immunohistochemistry

IHC analysis of Nav1.7 in mouse brain tissue using a dilution of SCN9A / Nav1.7 antibody.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
IHC analysis of Nav1.7 in mouse brain tissue using a dilution of SCN9A / Nav1.7 antibody. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Immunofluorescence

Nav1.7 (S68-6), Human hippocampus.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Nav1.7 (S68-6), Human hippocampus. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Immunofluorescence

Nav1.7 (S68-6), Mouse back skin.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Nav1.7 (S68-6), Mouse back skin. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

Nav1.7 (S68-6), T-CHO.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Nav1.7 (S68-6), T-CHO. This image was taken for the unconjugated form of this product. Other forms have not been tested.


Requested From: 
Date Requested: 6/21/2018

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