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Anti-SCN3A / Nav1.3 Antibody (Internal) IHC-plus™ LS-A8070

Ordering

Wt. Vol. Conc. Price
50 µg 50 µl 1 mg/ml Unavailable
Same day shipping In Stock - Same day shipping

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Rabbit Polyclonal to Human SCN3A / Nav1.3
Human
IHC - Paraffin
Unconjugated

Details

Human SCN3A / Nav1.3
Rabbit
Human (tested or 100% immunogen sequence identity)
Monkey (at least 90% immunogen sequence identity)
Polyclonal
Unconjugated
Immunoaffinity purified
Unmodified

Applications

IHC - Paraffin (15 - 20 µg/ml)

Specificity and Use

SCN3A / Nav1.3 antibody was raised against synthetic 18 amino acid peptide from internal region of human SCN3A / Nav1.3. Percent identity with other species by BLAST analysis: Human, Chimpanzee (100%); Monkey, Galago (94%); Orangutan, Gibbon, Marmoset, Mouse, Bovine, Guinea pig (89%); Rat, Hamster, Panda, Dog (83%).
LS-E29330 - Liquid - 50 µg - $145.00
Immunizing peptide used to generate LS-A8070. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Internal
Human SCN3A / Nav1.3. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Proteinase K antigen retrieval was used for Immunohistochemistry with formalin-fixed paraffin-embedded human tissues.

Packaging

PBS, less than 0.1% sodium azide.
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze thaw cycles.
For research use only.

About SCN3A / Nav1.3

Q9NY46 NM_006922 NP_008853.3

SCN3A Antibody, NAC3 Antibody, Nav1.3 Antibody, SCIII Antibody, Brain sodium channel III Antibody, KIAA1356 Antibody

Scn3a encodes the alpha subunit of the type III voltage-gated sodium channel. These channels, composed of one alpha and one or two beta subunits, mediate changes in cell permeability to sodium ions that are essential for the generation of action potentials. The alpha subunit alone has been shown to generate a functional channel in vitro, but it's kinetic properties are modulated by beta subunits. The type III channel has been shown to be tetrodotoxin sensitive and fast inactivated.

Immunohistochemistry

Immunohistochemistry
Anti-SCN3A / Nav1.3 antibody LS-A8070 IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
 

Requested From: 
Date Requested: 3/23/2017

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