Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
SCG10 / STMN2 is a member of the stathmin family of phosphoproteins. Stathmin proteins function in microtubule dynamics and signal transduction. The encoded protein plays a regulatory role in neuronal growth and is also thought to be involved in osteogenesis. Reductions in the expression of this gene have been associated with Down's syndrome and Alzheimer's disease. Alternatively spliced transcript variants have been observed for this gene.
STMN2 Antibody - Staining of STMN2 in HEK293T cells transfected with GFP or a GFP-STMN2 fusion. Antibody was used at a dilution of 1:1000 (A, B) and 1:3000 (C).
STMN2 Antibody - Staining of STMN2 in primary mouse dorsal root ganglia neurons. Shows the expected staining of endogenous STMN2 in axons and growth cones. Tubulin is a marker of axons. Antibody was used at a dilution of 1:4000.
STMN2 Antibody - Western blot of STMN2 in HEK293T cells transfected with GFP or a GFP-STMN2 fusion. Antibody was used at a dilution of 1:4000.
STMN2 Antibody - Western blot of endogenous STMN2 in mouse dorsal root ganglia (DRG) neurons. A partial siRNA knockdown was used in the second lane. Antibody was used at a dilution of 1:1000.