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Anti-SC5b-9 Antibody (clone 3R2/0) LS-C58185


Wt. Vol. Conc. Price
100 µg - 1 mg/ml $525
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)

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Anti-SC5b-9 Antibody (clone 3R2/0) LS-C58185
Mouse Monoclonal [clone 3R2/0] (IgG2b) to Human SC5b-9
IHC - Frozen, Western blot, Flow Cytometry, ELISA
Anti-SC5b-9 Antibody (clone aE11, FITC) LS-C210266
Mouse Monoclonal [clone aE11] (IgG2a) to Human SC5b-9
Human, Horse, Porcine
IHC - Paraffin, IHC - Frozen, Immunofluorescence, Flow Cytometry, Functional Assay
FITC Conjugated

100% Guaranteed 100% Guaranteed
Mouse Monoclonal [clone 3R2/0] (IgG2b) to Human SC5b-9
IHC - Frozen, Western blot, Flow Cytometry, ELISA


Human SC5b-9
Human (tested or 100% immunogen sequence identity)
IgG2b Monoclonal [3R2/0]
Affinity purified


  • IHC - Frozen
  • Western blot
  • Flow Cytometry

Specificity and Use

Recognizes the SC5b-9 complex of around 330 kD. Both the classical and alternative complement pathways result in the formation of the cytolysis inducing C5b-9 complex. This complex is composed of 190 kD C5b which is bound to cells via 71 kD C9. Sublytic assembly of C5b-9 on plasma membranes induces cell cycle activation and survival. The binding of C5b-9 to the 75 kD S-protein (or vitronectin) in the fluid phase prevents C5b-9 from assembling on the plasma membrane, deactivating it and forming the SC5b-9 complex. SC5b-9 is stable in vitro and is therefore a reliable indicator of terminal complement pathway activation. Removal of Sodium Azide is recommended prior to use in functional assays. Reported to work in western blotting applications.


Borate buffered saline, pH 8.4, <0.1% sodium azide.
Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.
For research use only.

About SC5b-9

Requested From: United States
Date Requested: 10/21/2016

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