LSBio
Products
  • Antibodies
  • All Antibodies
  • Primary Antibodies
  • Secondary Antibodies
  • IHC-plus Antibodies
  • Isotype Control Antibodies
  • ELISA and Assay Kits
  • All Kits
  • Assay Kits
  • Traditional ELISA Kits
  • Cell-Based ELISA Kits
  • DNA-Binding ELISA Kits
  • Phospho-Specific ELISA Kits
  • ELISA Development Kits
  • Chemiluminescent CLIA Kits
  • Proteins
  • All Proteins
  • Recombinant Proteins
  • Native Proteins
  • Over-expression Lysates
  • Cell and Tissue Lysates
  • Bio-active Proteins
  • Animal-free Proteins
  • Synthetic Peptides
  • Biochemicals
  • All Biochemicals

  • Immunohistochemistry
  • Comprehensive IHC Reports
  • Custom IHC Services
  • TCR Screening Services
  • IHC-plus Antibodies
Services
  • Immunohistochemistry Services

  • Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

  • TCR Screening Services

  • Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Have a question? CustomerSupport@LSBio.com
Resources
  • Purchasing
  • Product Ordering Terms and Conditions
  • Holiday Schedule
  • About the LSBio Guarantee
  • About Our Rewards Program
  • Reference Material
  • About LSBio (LifeSpan BioSciences Inc.)
  • About Our 2-million Specimen Tissue Bank
  • About Our IHC Validation Process
  • About Our IHC-plus™ Immunohistochemistry Protocol
  • Protocols
  • Secure Logins
  • Login to Our Secure ShareFile Site
  • Login to Our IHC Database
Distributors
Contact Us

LSBio
2401 Fourth Avenue Suite 900
Seattle WA 98121

Phone: 866-819-4732 (Toll Free North America)
206-374-1102 (International)

Fax: 866-206-6909 (Toll Free North America)
206-577-4565 (International)
How to Buy - Details about how to buy our products.

Orders@LSBio.com - To submit a new order.

Customer.Support@LSBio.com - To submit questions about existing orders, pricing, availability, bulk quotes, proforma invoice requests, or other billing issues.

Technical.Support@LSBio.com - To request technical information requests about an LSBio product or its application.

Sales@LSBio.com - To request information about fee-for-service contract IHC studies, IHC reports, distribution agreements, or general business development.

Worldwide Distributors List - To find your local distributor if you're not within the United States.
Login ▾
Wish List
View Cart

Anti-SC5b-9 Antibody (clone 3R2/0) LS-C58185

Catalog Size Price
LS-C58185-100 100 µg (1 mg/ml) Unavailable

Related Products

6 SC5b-9 Antibodies

Most Popular SC5b-9 Antibodies

Anti-SC5b-9 Antibody (clone 3R2/0) LS-C58185
Mouse Monoclonal [clone 3R2/0] (IgG2b) to Human SC5b-9
Human
IHC - Frozen, Western blot, Flow Cytometry, ELISA
Unconjugated
Anti-SC5b-9 Antibody (clone aE11, FITC) LS-C210266
Mouse Monoclonal [clone aE11] (IgG2a) to Human SC5b-9
Human, Horse, Pig
IHC - Paraffin, IHC - Frozen, Immunofluorescence, Flow Cytometry, Functional Assay
FITC Conjugated
Anti-SC5b-9 Antibody (Biotin) LS-C529480
Mouse Monoclonal (IgG2b) to Human SC5b-9
Human
IHC, Western blot, Flow Cytometry, ELISA
Biotin Conjugated
Anti-SC5b-9 Antibody (FITC) LS-C539399
Mouse Monoclonal (IgG2b) to Human SC5b-9
Human
IHC, Western blot, Flow Cytometry, ELISA
FITC Conjugated
Anti-SC5b-9 Antibody (PE) LS-C657544
Mouse Monoclonal (IgG2b) to Human SC5b-9
Human
IHC, Western blot, Flow Cytometry, ELISA
PE Conjugated

100% Guaranteed
Mouse Monoclonal [clone 3R2/0] (IgG2b) to Human SC5b-9
Human
IHC - Frozen, Western blot, Flow Cytometry, ELISA
Unconjugated

Details

Human SC5b-9
Mouse
Human (tested or 100% immunogen sequence identity)
IgG2b Monoclonal [3R2/0]
Unconjugated
Affinity purified
Unmodified

Applications

  • IHC - Frozen
  • Western blot
  • Flow Cytometry
  • ELISA

Specificity and Use

Recognizes the SC5b-9 complex of around 330 kD. Both the classical and alternative complement pathways result in the formation of the cytolysis inducing C5b-9 complex. This complex is composed of 190 kD C5b which is bound to cells via 71 kD C9. Sublytic assembly of C5b-9 on plasma membranes induces cell cycle activation and survival. The binding of C5b-9 to the 75 kD S-protein (or vitronectin) in the fluid phase prevents C5b-9 from assembling on the plasma membrane, deactivating it and forming the SC5b-9 complex. SC5b-9 is stable in vitro and is therefore a reliable indicator of terminal complement pathway activation. Removal of Sodium Azide is recommended prior to use in functional assays. Reported to work in western blotting applications.

Packaging

Borate buffered saline, pH 8.4, <0.1% sodium azide.
Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.
For research use only.

About SC5b-9


Requested From: 
Date Requested: 12/16/2017

Get Social With Us! Follow us on Facebook Follow us on Google+ Follow us on LinkedIn PSL Alliance Member
Copyright © 2017 LifeSpan BioSciences, Inc. All Rights Reserved Privacy Policy
Catalog Number