Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
SAR1B Antibody, ANDD Antibody, CMRD Antibody, GTP-binding protein SAR1b Antibody, GTP-binding protein Sara Antibody, SARB Antibody, SAR1a gene homolog 2 Antibody, SARA2 Antibody, GTBPB Antibody, GTP-binding protein B Antibody, SAR1 homolog B (S. cerevisiae) Antibody
SARA2 / SAR1B is a small GTPase that acts as a homodimer. The encoded protein is activated by the guanine nucleotide exchange factor PREB and is involved in protein transport from the endoplasmic reticulum to the Golgi. This protein is part of the COPII coat complex. Defects in this gene are a cause of chylomicron retention disease (CMRD), also known as Anderson disease (ANDD). Two transcript variants encoding the same protein have been found for this gene.
Anti-SARA2 / SAR1B antibody IHC staining of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B9636 concentration 10 ug/ml.
Western Blot: The extract of Mouse muscle (40 ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human SAR1B antibody (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody.