Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Human (tested or 100% immunogen sequence identity)
ICC (1:100 - 1:1000)
Western blot (1:500 - 1:3000)
Specificity and Use
SAFB1 / SAFB antibody was raised against recombinant protein fragment contain a sequence corresponding to a region within amino acids 476 and 695 (Q15424) of SAFB. Percent identity by BLAST analysis: Human (100%); Bovine (87%).
Human SAFB1 / SAFB
0.1 M Tris-glycine, pH 7.0, 10% glycerol, 0.01% Thimerosal
Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
SAFB Antibody, HAP Antibody, HET Antibody, Scaffold attachment factor B Antibody, SAB-B1 Antibody, SAFB1 Antibody, SAF-B Antibody, SAF-B1 Antibody, Scaffold attachment factor B1 Antibody, Hsp27 ERE-TATA binding protein Antibody, HSP27 ERE-TATA-binding protein Antibody
SAFB1 / SAFB is a DNA-binding protein which has high specificity for scaffold or matrix attachment region DNA elements (S/MAR DNA). This protein is thought to be involved in attaching the base of chromatin loops to the nuclear matrix but there is conflicting evidence as to whether this protein is a component of chromatin or a nuclear matrix protein. Scaffold attachment factors are a specific subset of nuclear matrix proteins (NMP) that specifically bind to S/MAR.