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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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SAE1 Antibody LS‑C17948
SAE1 antibody LS-C17948 is an unconjugated sheep polyclonal antibody to human SAE1. Validated for ICC and WB.
Antibody
Catalog
Size
Price
LS-C17948-50
50 µg
$455

Popular SAE1 Products

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Anti-SAE1 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B420 concentration 5 ug/ml.
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Immunohistochemical analysis of SAE1 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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Product Description

SAE1 antibody LS-C17948 is an unconjugated sheep polyclonal antibody to human SAE1. Validated for ICC and WB.
About SAE1
The heterodimer acts as a E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Q9UBE0 NM_005500 NP_005491.1

SAE1 Antibody, Activator of SUMO1 Antibody, AOS1 Antibody, UBLE1A Antibody, HSPC140 Antibody, SUA1 Antibody


Specifications

Target
Human SAE1
Host
Sheep
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • ICC
  • Western blot
Immunogen
SAE1 antibody was raised against bacterially produced and purified human SUMO-1 activating enzyme (subunit SAE1).
Specificity
Recognizes human SAE1.
Usage
Immunocytochemistry. Western Blot (1:3000).
Presentation
Affinity purified antibody in 50 mM Tris-HCl, pH 7.5, 100 mM sodium chloride, 1% BSA, 10% glycerol.
Storage
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: United States
Date Requested: 8/20/2018

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