The Immunohistochemistry Antibody Company
|Human, Monkey, Bat, Horse, Rabbit (tested or 100% immunogen sequence identity)|
|Bovine, Pig (at least 90% immunogen sequence identity)|
|SAE1 antibody was raised against synthetic peptide MKGNGIVECLGPK from the C-terminus of human SAE1 (NP_005491.1). Percent identity by BLAST analysis: Human, Gorilla, Orangutan, Monkey, Marmoset, Bat, Horse, Rabbit (100%); Panda, Bovine, Pig, Opossum (92%); Mouse, Rat, Elephant (85%).|
|Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide|
|Store at -20°C. Minimize freezing and thawing.|
|For research use only.|
SAE1 Antibody, Activator of SUMO1 Antibody, AOS1 Antibody, UBLE1A Antibody, HSPC140 Antibody, SUA1 AntibodyThe heterodimer acts as a E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2.