The Immunohistochemistry Antibody Company
|Human, Mouse, Rat (tested or 100% immunogen sequence identity)|
|SAE1 antibody was raised against synthetic peptide from human AOS1 (aa221-270).|
|AOS1 Antibody detects endogenous levels of total AOS1 protein.|
|PBS (without Mg2+, Ca2+), pH 7.4, 150 mM sodium chloride, 0.02% sodium azide, 50% glycerol|
|Store at -20°C for up to one year.|
|For research use only.|
SAE1 Antibody, Activator of SUMO1 Antibody, AOS1 Antibody, UBLE1A Antibody, HSPC140 Antibody, SUA1 AntibodyThe heterodimer acts as a E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2.