Human S1PR1 / EDG1 / S1P1

Rabbit

Human, Mouse, Rat (tested or 100% immunogen sequence identity)

IgG Polyclonal

Unconjugated

Protein A purified

Unmodified

A recombinant protein fragment from the C-Terminus portion of human EDG1.

C-Terminus

Human S1PR1 / EDG1 / S1P1.

• Western blot (4 - 6 µg/ml)

EDG1 (Endothelial differentiation gene 1), also called Sphingosine-1-phosphate receptor 1 (S1PR1) is the G-protein coupled receptor for Sphingosine 1-phosphate (S1P). Via its interaction with S1P, EDG1 is involved in a number of cellular processes. The binding of S1P leads to angiogenesis and tumor cell motility in cancer, and this interaction also participates in the formation of cell-cell adherens junctions. During embryogenesis, it regulates vascularization. EDG1 interacts with the serotonin receptor 5-HT1AR in the central nervous system. It is also a regulator of innate and adaptive immunity by signaling the release of T-cells from lymph nodes.

1X PBS, pH 7.4, 0.1 mg/ml BSA, 0.05% Sodium Azide

Store at -20°C. Avoid freeze-thaw cycles.

For research use only. Intended for use by laboratory professionals.

This antibody carries the LSBio 100% Guarantee.

Uniprot: P21453 NCBI: NM_001400 NP_001391.2