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Anti-S100A8 / MRP8 Antibody (clone 8-5C2, Biotin) LS-C96231

Ordering

Wt. Vol. Conc. Price
100 µg - - $545
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular S100A8 / MRP8 Antibodies

Anti-S100A8 / MRP8 Antibody (clone CF-145) IHC-plus™ LS-B1618
Mouse Monoclonal [clone CF-145] (IgG2b) to Human S100A8 / MRP8
Human
IHC - Paraffin, Immunofluorescence, Western blot, Flow Cytometry
Unconjugated
Immunohistochemistry Image
Anti-S100A8 / MRP8 Antibody (FITC) IHC-plus™ LS-B2247
Mouse Monoclonal (IgG1) to Human S100A8 / MRP8
Human, Monkey, Rat, Bovine, Cat, Dog, Horse, Pig, Rabbit
IHC - Paraffin, Flow Cytometry
FITC Conjugated
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Mouse Monoclonal [clone 8-5C2]
Human
IHC - Paraffin, ELISA
Biotin Conjugated

Details

S100A8 / MRP8
Mouse
Human (tested or 100% immunogen sequence identity)
Monoclonal [8-5C2]
Biotin
Affinity purified
Unmodified

Applications

  • IHC - Paraffin
  • ELISA

Specificity and Use

S100A8 / MRP8 antibody was raised against cultured human monocytes
The antigen is MRP8, the epitope is suspected in the central portion of the peptide. Antigen distribution: Isolated cells: The antigen is found in granulocytes and monocytes but not in other blood cells. In cultured monocytes, maximum MRP8 expression is found after 3 - 4 days. Myeloid leukaemia stains positively. Tissue sections: MRP8 is found in a distinct subpopulation of inflammatory perivascular infiltrates of the myelo-monocytic lineage. Macrophages synthesise MRP8 increasingly during the late stages of inflammation. A low MRP8 (and high MRP- 14) expression by macrophages was also reported in granulomatous diseases such as tuberculosis and sarcoidis. In non-granulomatous chronic inflammatory diseases such as chronic rheumatoid arthritis or chronic rejection after allograft transplantation, MRP8 and MRP14 positive cells consist of different subpopulations. Specificity: Human: MRP8 in stimulated monocytes and macrophages in late phase or chronic inflammation. Other: The antibody reacts with bovine spleen but does not react with rat tissues. It shows a diffuse reaction with swine spleen.
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Packaging

Lyophilized from PBS pH 7.2, 10mg/ml BSA, 0.01% thimerosal
0.5ml distilled water
Store at 4°C.
For research use only.

About S100A8 / MRP8

P05109 NM_002964 NP_002955.2

S100A8 Antibody, 60B8AG Antibody, CFAG Antibody, CAGA Antibody, Calgranulin A Antibody, Calgranulin-A Antibody, Calprotectin L1L subunit Antibody, Cystic fibrosis antigen Antibody, CGLA Antibody, L1Ag Antibody, NIF Antibody, p8 Antibody, Protein S100-A8 Antibody, MRP8 Antibody, Urinary stone protein band A Antibody, CP-10 Antibody, MA387 Antibody, MRP-8 Antibody

S100A8 is a calcium- and zinc-binding protein which plays a prominent role in the regulation of inflammatory processes and immune response. It can induce neutrophil chemotaxis and adhesion. Predominantly found as calprotectin (S100A8/A9) which has a wide plethora of intra- and extracellular functions.

Requested From: United States
Date Requested: 12/7/2016

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