Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Rabbit Polyclonal to Human RYR3 / Ryanodine Receptor 3
Human, Mouse, Rat
IHC - Paraffin, ICC, Western blot
Human RYR3 / Ryanodine Receptor 3
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
IHC - Paraffin (1:250)
Western blot (1:1000)
Specificity and Use
RYR3 / Ryanodine Receptor 3 antibody was raised against synthetic peptide from the variant TM region of human Ryanodine Receptor 3
Ryanodine Receptor 3
Western blot: 1:1000 using ECL. The antibody reacts with the 500 kD Ryanodine Receptor 3 protein. Suggested blocking buffer is 10% normal goat serum (or same host as your secondary antibody), 1% BSA in 0.1 M PBS with 0.05% Tween 20. Suggested dilution buf
Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.
Calcium channel that mediates the release of Ca2+ from the sarcoplasmic reticulum into the cytoplasm in muscle and thereby plays a role in triggering muscle contraction. May regulate Ca2+ release by other calcium channels. Calcium channel that mediates Ca2+-induced Ca2+ release from the endoplasmic reticulum in non-muscle cells. Contributes to cellular calcium ion homeostasis (By similarity). Plays a role in cellular calcium signaling.