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RYBP

RING1 and YY1 binding protein

Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands. Cell death signals are transduced by death domain (DD) death effector domain (DED), and caspase recruitment domain (CARD) containing molecules. Several molecules including caspases and adaptor FADD contain DEDs. A novel protein that interacts with DED of caspase-8 and -10, and FADD was identified recently and designated DEDAF for DED associated factor. DEDAF is identical to the transcriptional repressor RYBP. DEDAF/RYBP is expressed in multiple tissues and cell lines. DEDAF interacts with FADD and augments the formation of CD95/FADD/caspase-8 complexes at the cell membrane, and interacts with DED-containing DNA biding protein (DEDD) in the nucleus indicating it is involved in the regulation of both cytoplasmic and nuclear events of apoptosis.

Gene Name: RING1 and YY1 binding protein
Family/Subfamily: Apoptosis
Synonyms: RYBP, AAP1, APAP-1, Apoptin-associating protein 1, DED-associated factor, DEDAF, Ring1 interactor RYBP, RING1 and YY1 binding protein, YEAF1, RING1 and YY1-binding protein
Target Sequences: NM_012234 NP_036366.3 Q8N488

☰ Filters
Antibodies (51)
Proteins (5)
ELISA Kits (1)
Over-Expression Lysate (2)
Primary (51)
Recombinant (3)
Sandwich (1)
RYBP (57)
Human (50)
Mouse (20)
Rat (16)
Bovine (6)
Chicken (3)
Chimpanzee (9)
Dog (8)
Gibbon (6)
Guinea pig (6)
Horse (6)
Monkey (8)
Pig (6)
Rabbit (6)
Xenopus (6)
Zebrafish (6)
IHC (11)
IHC-P (11)
WB (51)
Flo (4)
ELISA (8)
IF (5)
IP (1)
Peptide-ELISA (1)
rabbit (33)
mouse (18)
Product Group
IHCPlus (3)
IgG (19)
IgG1 (18)
monoclonal mc (18)
polyclonal pc (33)
OTI1B2 (2)
OTI1B6 (2)
OTI2B4 (2)
OTI2D4 (2)
OTI2F6 (2)
OTI2H9 (2)
OTI4E10 (2)
OTI5A9 (2)
OTI7D1 (2)
96-Well Strip Plate (1)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (6)
Carrier-free (9)
FITC Conjugated (6)
HRP Conjugated (6)
PE Conjugated (2)
Unconjugated (30)
aa1-30 (7)
C-Terminus (4)
N-Terminus (4)
aa56-105 (4)
aa71-120 (4)
aa131-165 (1)
aa215-228 (1)
No (56)
Yes (1)
Cell Lysates (1)
Tissue Homogenates (1)
GST (1)
His (1)
Myc-DDK (Flag) (3)
Human (4)
293T Cells (1)
E. coli (1)
HEK 293 Cells (2)
Wheat Germ Extract (1)
Purified (2)
RYBP Antibody - Anti-RYBP antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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RYBP Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
0.05 mg/$460
RYBP Antibody - Fetal muscle lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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RYBP Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$424
RYBP Antibody - Anti-RYBP antibody IHC of human thyroid. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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RYBP Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
RYBP Antibody - Anti-RYBP antibody IHC of human thyroid. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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RYBP Rabbit anti-Human Polyclonal (N-Terminus) (HRP) Antibody
Xenopus, Zebrafish, Mouse, Human, Chimpanzee
IHC, IHC-P, WB
HRP Conjugated
100 µl/$469
RYBP Antibody - Anti-RYBP antibody IHC of human thyroid. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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RYBP Rabbit anti-Human Polyclonal (N-Terminus) (Biotin) Antibody
Xenopus, Zebrafish, Mouse, Human, Chimpanzee
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$469
RYBP Antibody - Anti-RYBP antibody IHC of human thyroid. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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RYBP Rabbit anti-Human Polyclonal (N-Terminus) (FITC) Antibody
Xenopus, Zebrafish, Mouse, Human, Chimpanzee
IHC, IHC-P, WB
FITC Conjugated
100 µl/$469
RYBP Antibody - Anti-RYBP mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY RYBP.
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RYBP Mouse anti-Human Monoclonal (OTI4E10) Antibody
Human
IF, WB
Unconjugated
100 µl/$434
RYBP Antibody - Anti-RYBP mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY RYBP.
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RYBP Mouse anti-Human Monoclonal (Carrier-free) (OTI4E10) Antibody
Human
IF, WB
Unconjugated, Carrier-free
100 µg/$511
RYBP Antibody - IHC of paraffin-embedded Human colon tissue using anti-RYBP mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min).
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RYBP Mouse anti-Human Monoclonal (OTI1B2) Antibody
Human
IF, IHC, IHC-P, WB
Unconjugated
100 µl/$434
RYBP Antibody - IHC of paraffin-embedded Human colon tissue using anti-RYBP mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min).
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RYBP Mouse anti-Human Monoclonal (Carrier-free) (OTI1B2) Antibody
Human
IF, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
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RYBP Rabbit anti-Human Polyclonal (aa215-228) Antibody
Mouse, Rat, Human
WB
Unconjugated
100 µg/$729
RYBP Antibody - Anti-RYBP antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
RYBP Rabbit anti-Human Polyclonal (aa71-120) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
RYBP Antibody - Anti-RYBP antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
RYBP Rabbit anti-Human Polyclonal (aa71-120) (HRP) Antibody
Rabbit, Dog, Guinea pig, Bovine, Rat, Pig, Horse, Gibbon, Chimpanzee, Human, Monkey
IHC, IHC-P, WB
HRP Conjugated
100 µl/$469
RYBP Antibody - Anti-RYBP antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
RYBP Rabbit anti-Human Polyclonal (aa71-120) (Biotin) Antibody
Rabbit, Dog, Guinea pig, Bovine, Rat, Pig, Horse, Gibbon, Chimpanzee, Human, Monkey
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$469
RYBP Antibody - Anti-RYBP antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
RYBP Rabbit anti-Human Polyclonal (aa71-120) (FITC) Antibody
Rabbit, Dog, Guinea pig, Bovine, Rat, Pig, Horse, Gibbon, Chimpanzee, Human, Monkey
IHC, IHC-P, WB
FITC Conjugated
100 µl/$469
RYBP Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY RYBP (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-RYBP.
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RYBP Mouse anti-Human Monoclonal (OTI2H9) Antibody
Human
Flo, WB
Unconjugated
100 µl/$434
RYBP Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY RYBP (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-RYBP.
Select
RYBP Mouse anti-Human Monoclonal (Carrier-free) (OTI2H9) Antibody
Human
Flo, WB
Unconjugated, Carrier-free
100 µg/$511
RYBP Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY RYBP (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-RYBP.
Select
RYBP Mouse anti-Human Monoclonal (OTI1B6) Antibody
Human
Flo, WB
Unconjugated
100 µl/$434
RYBP Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY RYBP (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-RYBP.
Select
RYBP Mouse anti-Human Monoclonal (Carrier-free) (OTI1B6) Antibody
Human
Flo, WB
Unconjugated, Carrier-free
100 µg/$511
Select
RYBP Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IP, WB
Unconjugated
100 µg/$341
Select
RYBP Rabbit anti-Human Polyclonal (aa1-30) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
Select
RYBP Rabbit anti-Human Polyclonal (aa1-30) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
Select
RYBP Rabbit anti-Human Polyclonal (aa1-30) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
RYBP Antibody - Anti-Rybp Antibody at 1:2000 dilution + NIH/3T3 whole cell lysates Lysates/proteins at 20 ug per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution Predicted band size : 25 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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RYBP Rabbit anti-Mouse Polyclonal (aa131-165) Antibody
Mouse
Peptide-ELISA, WB
Unconjugated
400 µl/$393
Select
RYBP Rabbit anti-Human Polyclonal Antibody
Human
IHC-P, WB
Unconjugated
0.1 mg/$470
Viewing 1-25 of 57 product results



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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).