Human Ryanodine Receptor

Mouse

Human (tested or 100% immunogen sequence identity)

IgG2b Monoclonal

RYR.1 (G-1)

Unconjugated

Purified

Unmodified

Short synthetic polypeptide corresponding to the C-Terminus domain of the ryanodine receptor.

C-Terminus

Reacts with the C-terminus cytoplasmic domain of ryanodine receptor. Ryanodine receptors have been shown to play critical roles in the intracellular Ca2+ signaling occurring during cell activation in muscle cells and non-muscle cells. Reacts with ryanodine receptor (MW approx. 500kD) isolated from a variety of cell types (e. g. lymphocytes, macrophages, granulocytes, fibroblasts, epithelial, endothelial cells, skeletal muscle, cardiac muscle and brain tissues).

• IHC - Frozen (1:100)
• Immunofluorescence (1:100)
• Western blot (1:100)
• Flow Cytometry (1:500)
• ELISA (1:1000)

Immunohistology: Use indirect immunofluorescence. Visualization by confocal microscopy is required, as detection by standard fluorescent microscopy will not be adequate to detect the RyR. Additionally, fluorescent, not enzymatic, detection is required.

PBS, 0.01% Sodium Azide

Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.

For research use only. Intended for use by laboratory professionals.

This antibody carries the LSBio 100% Guarantee.