Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Human (tested or 100% immunogen sequence identity)
Protein G purified
Specificity and Use
RUNX3 antibody was raised against synthetic peptide corresponding to the middle region of human RUNX3.
Recognizes human RUNX3.
Suitable for use in Western Blot.
PBS, pH 7.4, 1% BSA, 0.05% sodium azide
May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C.
RUNX3 Antibody, Acute myeloid leukemia gene 2 Antibody, CBF-alpha-3 Antibody, PEA2 alpha C Antibody, PEBP2 alpha C Antibody, PEBP2-alpha C Antibody, PEBP2A3 Antibody, PEBP2aC Antibody, AML2 Antibody, Oncogene AML-2 Antibody, CBFA3 Antibody, PEA2-alpha C Antibody, Transcription factor AML2 Antibody
RUNX3 is a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer.