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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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RUNX1T1 / ETO Antibody (aa221‑270) LS‑C31287 Best Seller
ETO antibody LS-C31287 is an unconjugated rabbit polyclonal antibody to ETO (RUNX1T1) from human, mouse, rat and other species. Validated for WB.
Catalog
Size
Price
LS-C31287-100
100 µg (1 mg/ml)
Unavailable

Popular RUNX1T1 / ETO Products

RUNX1T1 antibody LS-C112160 Western blot of 293T cell lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Applications: Western blot
Immunofluorescence of monoclonal antibody to RUNX1T1 on HeLa cell . [antibody concentration 10 ug/ml]
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Product Description

ETO antibody LS-C31287 is an unconjugated rabbit polyclonal antibody to ETO (RUNX1T1) from human, mouse, rat and other species. Validated for WB.
About RUNX1T1 / ETO
RUNX1T1 / ETO is a member of the myeloid translocation gene family which interact with DNA-bound transcription factors and recruit a range of corepressors to facilitate transcriptional repression. The t(8;21)(q22;q22) translocation is one of the most frequent karyotypic abnormalities in acute myeloid leukemia. The translocation produces a chimeric gene made up of the 5'-region of the runt-related transcription factor 1 gene fused to the 3'-region of this gene. Q06455 NM_004349 NP_004340.1

RUNX1T1 Antibody, AML1T1 Antibody, CBFA2T1 Antibody, CDR Antibody, Eight twenty one protein Antibody, Cyclin-D-related protein Antibody, ETO Antibody, MTG8 Antibody, Protein CBFA2T1 Antibody, Protein ETO Antibody, ZMYND2 Antibody, Protein MTG8 Antibody


Specifications

Target
Human RUNX1T1 / ETO
Host
Rabbit
Reactivity
Human, Monkey, Mouse, Rat, Bat, Dog, Guinea pig, Horse, Pig, Rabbit, Chicken, Zebrafish (tested or 100% immunogen sequence identity)
Predicted
Xenopus (at least 90% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated. Also available conjugated with Biotin, FITC, HRP.
Purification
Protein A purified
Modifications
Unmodified
Applications
  • Western blot (1.25 µg/ml)
  • (applications tested for the base form of this product only)
Immunogen
RUNX1T1 / ETO antibody was raised against synthetic peptide located between aa221-270 of human RUNX1T1 (Q06455, NP_783554). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Monkey, Galago, Marmoset, Mouse, Rat, Elephant, Panda, Dog, Bat, Rabbit, Horse, Pig, Opossum, Guinea pig, Turkey, Chicken, Lizard, Stickleback, Zebrafish (100%); Xenopus (92%); Platypus (85%).
Blocking Peptide
LS-E12027 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-C31287. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Epitope
aa221-270
Specificity
Human RUNX1T1
Presentation
Lyophilized from PBS with 2% sucrose
Reconstitution
100 µl After adding water, will consist of PBS buffer with 2% sucrose
Storage
Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year); Short term (less than 1 week): 4°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Western blot

HepG2 Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
HepG2 Cell Lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

HepG2 Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
HepG2 Cell Lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

HepG2 Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
HepG2 Cell Lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

HepG2 Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
HepG2 Cell Lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.


Requested From: 
Date Requested: 6/21/2018

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