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Anti-RSPO3 Antibody (clone 400404) LS-C38971


Wt. Vol. Conc. Price
100 µg 200 µl - Unavailable

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24 RSPO3 Antibodies

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Anti-RSPO3 Antibody (clone 400404) LS-C38971
Rat Monoclonal [clone 400404] (IgG2a) to Mouse RSPO3
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Anti-RSPO3 Antibody (aa181-193) LS-C139710
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Anti-RSPO3 Antibody (C-Terminus) LS-C336277
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Anti-RSPO3 Antibody (aa22-272, clone 3A9) LS-C339260
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Anti-RSPO3 Antibody LS-C380096
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100% Guaranteed 100% Guaranteed
Rat Monoclonal [clone 400404] (IgG2a) to Mouse RSPO3
Western blot, ELISA


Mouse RSPO3
Mouse (tested or 100% immunogen sequence identity)
IgG2a Monoclonal [400404]
Protein G purified


  • Western blot

Specificity and Use

RSPO3 antibody was raised against e. coli-derived rmRSPO-3.
Selected for its ability to detect recombinant mouse RSPO-3 in direct ELISAs and Western Blots. In these formats, this antibody shows no cross-reactivity with rmRSPO-1, rmRSPO-4, rhRSPO-2, or rhRSPO-3.
Western Blot: This antibody can be used at 1-2 ug/ml with the appropriate secondary reagents to detect mouse RSPO-3. Using a colorimetric detection system, the detection limit for rmRSPO-3 is approximately 25 ng/lane under non-reducing and reducing conditions. Chemiluminescent detection will increase sensitivity by 5 to 50 fold. Direct ELISA: This antibody can be used at 0.5-1.0 ug/ml with the appropriate secondary reagents to detect mouse RSPO-3. The detection limit for rmRSPO-3 is approximately 1 ng/well.


Lyophilized from PBS with 5% trehalose
200 µl Sterile PBS
Store at -20°C prior to reconstitution. After reconstitution aliquot and freeze at-20°C. Avoid frequent freeze thaws.
For research use only.

About RSPO3

Q9BXY4 NM_032784 NP_116173.2

RSPO3 Antibody, CRISTIN1 Antibody, HRspo3 Antibody, HPWTSR Antibody, R-spondin 3 Antibody, Protein with TSP type-1 repeat Antibody, R-spondin 3 homolog Antibody, THSD2 Antibody, PWTSR Antibody, R-spondin-3 Antibody, Roof plate-specific spondin-3 Antibody

Activator of the canonical Wnt signaling pathway by acting as a ligand for LGR4-6 receptors. Upon binding to LGR4-6 (LGR4, LGR5 or LGR6), LGR4-6 associate with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes.

Requested From: 
Date Requested: 4/25/2017

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