RSPO3

R-spondin 3

Activator of the canonical Wnt signaling pathway by acting as a ligand for LGR4-6 receptors. Upon binding to LGR4-6 (LGR4, LGR5 or LGR6), LGR4-6 associate with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. Also regulates the canonical Wnt/beta-catenin-dependent pathway and non-canonical Wnt signaling by acting as an inhibitor of ZNRF3, an important regulator of the Wnt signaling pathway. Acts as a ligand for frizzled FZD8 and LRP6. May negatively regulate the TGF-beta pathway.

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Products

Antibodies (31)

ELISA Kits (7)

Proteins (7)

Type

Custom (1)

Over-Expression Lysate (2)

Primary (31)

Recombinant (5)

Sandwich (6)

Target

RSPO3 (45)

Reactivity

Human (34)

Mouse (10)

Rat (4)

Chimpanzee (3)

Pig (8)

Application

IHC (6)

IHC-P (2)

WB (24)

ELISA (8)

ICC (1)

IF (2)

Neut (1)

Peptide-ELISA (2)

Host

rabbit (23)

mouse (6)

rat (1)

sheep (1)

Product Group

IHCPlus (1)

Isotype

IgG (10)

IgG1 (6)

IgG2a (1)

Clonality

monoclonal mc (7)

polyclonal pc (24)

Clone

3D5 (2)

400404 (1)

OTI3A9 (2)

OTI4G10 (2)

Format

96-Well Microplate (1)

96-Well Strip Plate (6)

APC (1)

APC Conjugated (1)

Biotin Conjugated (3)

Carrier-free (3)

Cy3 Conjugated (1)

Cy7 Conjugated (1)

FITC Conjugated (3)

HRP Conjugated (3)

PE Conjugated (1)

Unconjugated (18)

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Epitope

aa22-272 (17)

aa202-251 (4)

aa214-248 (1)

Publications

No (45)

Sample Type

Cell Culture Supernatants (3)

Cell Lysates (3)

Plasma (5)

Serum (5)

Tissue Homogenates (2)

Tag

Fc/6His,C-terminus (1)

Fc-6His, C-terminus (1)

His (1)

His-T7 (1)

Myc-DDK (Flag) (2)

Species

Human (6)

Source

293T Cells (1)

CHO Cells (1)

E. coli (1)

HEK 293 Cells (1)

Human Cells (2)

Mammalian Cells (1)

Purification

Purified (2)

Low Endotoxin Level

Low endotoxin level (4)

Biologically Active

Biologically active (1)

Select

Human RSPO3 (Sandwich ELISA) ELISA Kit - LS-F39944

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

15.6 - 1000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Plasma, Serum

Price:

1 Plate/$1,150

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Human RSPO3 (Sandwich ELISA) ELISA Kit - LS-F7210

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.312 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$902

Select

RSPO3 Antibody LS-C336277

Antibody:

RSPO3 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, ICC, IF, IHC, WB

Format:

Unconjugated

Price:

0.1 mg/$460

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RSPO3 Antibody (aa22-272, clone OTI3A9) LS-C339260

Antibody:

RSPO3 Mouse anti-Human Monoclonal (aa22-272) (OTI3A9) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$434

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RSPO3 Antibody (aa22-272, clone OTI3A9, Carrier-free) LS-C790333

Antibody:

RSPO3 Mouse anti-Human Monoclonal (aa22-272) (Carrier-free) (OTI3A9) Antibody

Reactivity:

Human

Applications:

IHC, WB

Format:

Unconjugated, Carrier-free

Price:

100 µg/$511

• Unconjugated
• Unconjugated, Carrier-free

• Unconjugated
• Unconjugated, Carrier-free

Select

RSPO3 Antibody (clone 400404) LS-C38971

Antibody:

RSPO3 Rat anti-Mouse Monoclonal (400404) Antibody

Reactivity:

Mouse

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$884

Select

Mouse RSPO3 (Sandwich ELISA) ELISA Kit - LS-F39943

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

15.6 - 1000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Plasma, Serum

Price:

1 Plate/$1,150

Select

RSPO3 Antibody (aa22-272) LS-C753933

Antibody:

RSPO3 Rabbit anti-Human Polyclonal (aa22-272) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µg/$404

Select

IHC-plus™ RSPO3 Antibody (aa22-272, clone 3D5) LS-B12940

(4.0) Rating

Antibody:

RSPO3 Mouse anti-Human Monoclonal (aa22-272) (3D5) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P

Format:

Unconjugated

Price:

100 µl/$485

Select

RSPO3 Antibody LS-C398112

Antibody:

RSPO3 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

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RSPO3 Antibody (aa22-272, HRP) LS-C398050

Antibody:

RSPO3 Rabbit anti-Human Polyclonal (aa22-272) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

HRP Conjugated

Price:

50 µg/$294; 100 µg/$360

Select

RSPO3 Antibody (Biotin) LS-C397958

Antibody:

RSPO3 Rabbit anti-Human Polyclonal (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

Biotin Conjugated

Price:

50 µg/$294; 100 µg/$360

Select

RSPO3 Antibody (FITC) LS-C397957

Antibody:

RSPO3 Rabbit anti-Human Polyclonal (FITC) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

FITC Conjugated

Price:

50 µg/$294; 100 µg/$360

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

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RSPO3 Antibody (aa22-272) LS-C373790

Antibody:

RSPO3 Rabbit anti-Human Polyclonal (aa22-272) Antibody

Reactivity:

Pig, Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$319; 200 µl/$365; 500 µl/$519; 1 ml/$597; 2 ml/$826; 5 ml/$1,352

Select

RSPO3 Antibody (aa22-272, clone 3D5, Carrier-free) LS-C798184

Antibody:

RSPO3 Mouse anti-Human Monoclonal (aa22-272) (Carrier-free) (3D5) Antibody

Reactivity:

Human

Applications:

IHC

Format:

Unconjugated, Carrier-free

Price:

100 µg/$511

Select

RSPO3 Antibody LS-C803137

Antibody:

RSPO3 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

Select

RSPO3 Antibody LS-C779874

Antibody:

RSPO3 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$357

Select

RSPO3 Antibody (aa214-248) LS-C393111

Antibody:

RSPO3 Rabbit anti-Human Polyclonal (aa214-248) Antibody

Reactivity:

Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

200 µl/$393

Select

RSPO3 Antibody (aa22-272, clone OTI4G10) LS-C339384

Antibody:

RSPO3 Mouse anti-Human Monoclonal (aa22-272) (OTI4G10) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$434

Select

RSPO3 Antibody (aa22-272, clone OTI4G10, Carrier-free) LS-C790436

Antibody:

RSPO3 Mouse anti-Human Monoclonal (aa22-272) (Carrier-free) (OTI4G10) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated, Carrier-free

Price:

100 µg/$511

• Unconjugated
• Unconjugated, Carrier-free

• Unconjugated
• Unconjugated, Carrier-free

Select

RSPO3 Antibody LS-C770392

Antibody:

RSPO3 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

Select

RSPO3 Antibody LS-C409925

Antibody:

RSPO3 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

Select

RSPO3 Antibody (aa202-251) LS-C170341

Antibody:

RSPO3 Rabbit anti-Human Polyclonal (aa202-251) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

Select

RSPO3 Antibody (aa202-251, FITC) LS-C467786

Antibody:

RSPO3 Rabbit anti-Human Polyclonal (aa202-251) (FITC) Antibody

Reactivity:

Human, Chimpanzee

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• FITC

• Unconjugated
• FITC

Select

RSPO3 Antibody (aa22-272) LS-C184886

Antibody:

RSPO3 Sheep anti-Human Polyclonal (aa22-272) Antibody

Reactivity:

Human

Applications:

Neut

Format:

Unconjugated

Price:

100 µg/$930

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