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RSPO2

R-spondin 2

Activator of the canonical Wnt signaling pathway by acting as a ligand for LGR4-6 receptors. Upon binding to LGR4-6 (LGR4, LGR5 or LGR6), LGR4-6 associate with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. Also regulates the canonical Wnt/beta-catenin-dependent pathway and non-canonical Wnt signaling by acting as an inhibitor of ZNRF3, an important regulator of the Wnt signaling pathway. Probably also acts as a ligand for frizzled and LRP receptors.

Gene Name: R-spondin 2
Synonyms: RSPO2, CRISTIN2, R-spondin 2, R-spondin 2 homolog, R-spondin-2, HRspo2, Roof plate-specific spondin-2
Target Sequences: NM_178565 NP_848660.3 Q6UXX9

☰ Filters
Antibodies (9)
Proteins (4)
Over-Expression Lysate (2)
Primary (9)
Recombinant (2)
RSPO2 (13)
Human (9)
Mouse (2)
Rat (1)
IHC (7)
IHC-P (1)
WB (9)
Flo (7)
ELISA (8)
IP (1)
rabbit (9)
IgG (7)
polyclonal pc (9)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (1)
FITC Conjugated (1)
HRP Conjugated (1)
PE Conjugated (1)
Unconjugated (4)
aa190-218 (7)
aa22-243 (1)
No (13)
GST (1)
Myc-DDK (Flag) (2)
Human (3)
293T Cells (1)
CHO Cells (1)
HEK 293 Cells (1)
Wheat Germ Extract (1)
Purified (2)
Low endotoxin level (1)
Biologically active (1)
RSPO2 Antibody - RSPO2 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human lung carcinoma followed by peroxidase-conjugated secondary antibody and DAB staining.
Select
RSPO2 Rabbit anti-Human Polyclonal (aa190-218) Antibody
Human
Flo, IHC, IHC-P, WB
Unconjugated
400 µl/$393
Select
RSPO2 Rabbit anti-Human Polyclonal (aa22-243) Antibody
Mouse, Rat, Human
ELISA, IP, WB
Unconjugated
100 µg/$341
Select
RSPO2 Rabbit anti-Human Polyclonal (aa190-218) Antibody
Human
ELISA, Flo, IHC, WB
Unconjugated
200 µl/$734
Select
RSPO2 Rabbit anti-Human Polyclonal (aa190-218) (Biotin) Antibody
Human
ELISA, Flo, IHC, WB
Biotin Conjugated
200 µl/$952
Select
RSPO2 Rabbit anti-Human Polyclonal (aa190-218) (FITC) Antibody
Human
ELISA, Flo, IHC, WB
FITC Conjugated
200 µl/$952
Select
RSPO2 Rabbit anti-Human Polyclonal (aa190-218) (APC) Antibody
Human
ELISA, Flo, IHC, WB
APC Conjugated
200 µl/$952
Select
RSPO2 Rabbit anti-Human Polyclonal (aa190-218) (Azide-free) (HRP) Antibody
Human
ELISA, Flo, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
Select
RSPO2 Rabbit anti-Human Polyclonal (aa190-218) (PE) Antibody
Human
ELISA, Flo, IHC, WB
PE Conjugated
200 µl/$952
Select
RSPO2 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, WB
Unconjugated
100 µg/$357
RSPO2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
28.1 kDa
20 µg/$150
RSPO2 Protein - 12.5% SDS-PAGE of human RSPO2 stained with Coomassie Blue
Select
Wheat Germ Extract
GST
46.8 kDa
2 µg/$439
RSPO2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
28.1 kDa
100 µg/$494
Select
CHO Cells
None
Biologically active
Less than 0.1 ng/µg of protein (less than 1EU/µg).
24.4 kDa
5 µg/$268; 20 µg/$349
Viewing 1-13 of 13 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).