RSPO1 / RSPO

R-spondin 1

Activator of the canonical Wnt signaling pathway by acting as a ligand for LGR4-6 receptors. Upon binding to LGR4-6 (LGR4, LGR5 or LGR6), LGR4-6 associate with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. Also regulates the canonical Wnt/beta-catenin-dependent pathway and non-canonical Wnt signaling by acting as an inhibitor of ZNRF3, an important regulator of the Wnt signaling pathway. Acts as a ligand for frizzled FZD8 and LRP6. May negatively regulate the TGF-beta pathway. Has a essential roles in ovary determination.

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Products

Antibodies (51)

Proteins (14)

ELISA Kits (10)

Type

Custom (1)

Development Kit (1)

Over-Expression Lysate (2)

Primary (51)

Recombinant (12)

Sandwich (8)

Target

RSPO1 / RSPO (75)

Reactivity

Human (31)

Mouse (17)

Rat (19)

Application

IHC (7)

IHC-P (5)

WB (46)

ELISA (6)

IF (1)

Neut (1)

Peptide-ELISA (1)

Host

rabbit (39)

mouse (11)

sheep (1)

Product Group

DevKit DuoPlus (1)

IHCPlus (2)

Isotype

IgG (6)

IgG1 (7)

IgG2a (2)

IgG2b (2)

Clonality

monoclonal mc (11)

polyclonal pc (40)

Clone

7A6 (2)

OTI11A9 (2)

OTI1C3 (2)

OTI2B11 (2)

OTI2F10 (2)

Format

96-Well Strip Plate (9)

Antibody Pair and Standard (1)

APC (4)

APC Conjugated (4)

Biotin Conjugated (4)

Carrier-free (4)

Cy3 Conjugated (4)

Cy7 Conjugated (4)

FITC Conjugated (4)

HRP Conjugated (4)

PE Conjugated (4)

Preservative Free (1)

Unconjugated (23)

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Epitope

aa21-135 (24)

aa21-263 (9)

aa136-262 (8)

aa206-240 (1)

aa31-263 (1)

Publications

No (75)

Sample Type

Cell Culture Supernatants (3)

Cell Lysates (3)

Plasma (7)

Serum (7)

Tissue Homogenates (6)

Tag

6His, C-terminus (2)

His (2)

His, N-Terminal (2)

His,C-terminus (2)

His-T7 (1)

Myc-DDK (Flag) (2)

Species

Human (8)

Mouse (3)

Rat (2)

Source

293T Cells (1)

CHO Cells (3)

E. coli (4)

HEK 293 Cells (2)

Human Cells (2)

Mammalian Cells (2)

Purification

Purified (5)

Low Endotoxin Level

Low endotoxin level (7)

Biologically Active

Biologically active (2)

Select

RSPO1 / RSPO Antibody LS-B4605

Antibody:

RSPO1 / RSPO Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

0.05 mg/$460

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RSPO1 / RSPO Antibody (aa21-263) LS-C377603

Antibody:

RSPO1 / RSPO Rabbit anti-Human Polyclonal (aa21-263) Antibody

Reactivity:

Human

Applications:

ELISA, IHC-P

Format:

Unconjugated

Price:

50 µl/$294; 100 µl/$360

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Mouse RSPO1 / RSPO Protein (Recombinant His) (aa21-135) - LS-G16201

Source:

E. coli

Tag:

His

Molecular Weight:

14.2 kDa

Price:

10 µg/$283; 50 µg/$452; 100 µg/$722; 200 µg/$902; 1 mg/$2,016; 500 µg/$1,553; 5 mg/$3,151; 2 mg/$2,204

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Human RSPO1 / RSPO (Sandwich ELISA) ELISA Kit - LS-F31680

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

31.2 - 2000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum

Price:

1 Plate/$717

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Mouse RSPO1 / RSPO (Sandwich ELISA) ELISA Kit - LS-F7110

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Tissue Homogenates

Price:

1 Plate/$923

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Human RSPO1 / RSPO (Sandwich ELISA) ELISA Kit - LS-F13432

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

78 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$783

Select

RSPO1 / RSPO Antibody (aa21-135) LS-C315031

Antibody:

RSPO1 / RSPO Rabbit anti-Human Polyclonal (aa21-135) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$319; 200 µl/$365; 500 µl/$519; 1 ml/$597; 2 ml/$826; 5 ml/$1,352

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RSPO1 / RSPO Antibody (aa21-135, HRP) LS-C714584

Antibody:

RSPO1 / RSPO Rabbit anti-Human Polyclonal (aa21-135) (HRP) Antibody

Reactivity:

Human

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$351; 200 µl/$411; 500 µl/$618; 1 ml/$774; 2 ml/$1,010; 5 ml/$1,757

• Unconjugated
• HRP

• Unconjugated
• HRP

Select

IHC-plus™ RSPO1 / RSPO Antibody LS-B14917

(4.0) Rating

Antibody:

RSPO1 / RSPO Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$460

Select

Mouse RSPO1 / RSPO (Sandwich ELISA) ELISA Kit - LS-F53365

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

6.25 - 400 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$958

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Mouse RSPO1 / RSPO (Sandwich ELISA) ELISA Kit - LS-F38945

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

15.6 - 1000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$996

Select

RSPO1 / RSPO Antibody (aa21-135) LS-C296288

Antibody:

RSPO1 / RSPO Rabbit anti-Mouse Polyclonal (aa21-135) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$321; 200 µl/$369; 500 µl/$527; 1 ml/$611; 2 ml/$842; 5 ml/$1,387

Select

Human RSPO1 / RSPO (Sandwich ELISA) ELISA Kit - LS-F34268

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

78.125 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$768

Select

Human RSPO1 / RSPO (Sandwich ELISA) ELISA Kit - LS-F6893

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

15.63 - 1000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$902

Select

RSPO1 / RSPO Antibody (aa21-263, clone OTI11A9) LS-C339254

Antibody:

RSPO1 / RSPO Mouse anti-Human Monoclonal (aa21-263) (OTI11A9) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$434

Select

RSPO1 / RSPO Antibody (aa21-263, clone OTI11A9, Carrier-free) LS-C798179

Antibody:

RSPO1 / RSPO Mouse anti-Human Monoclonal (aa21-263) (Carrier-free) (OTI11A9) Antibody

Reactivity:

Human

Applications:

IHC, WB

Format:

Unconjugated, Carrier-free

Price:

100 µg/$511

• Unconjugated
• Unconjugated, Carrier-free

• Unconjugated
• Unconjugated, Carrier-free

Select

RSPO1 / RSPO Antibody LS-C814073

Antibody:

RSPO1 / RSPO Mouse anti-Human Monoclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

50 µg/$332; 100 µg/$404; 200 µg/$505

Select

Human RSPO1 / RSPO (Sandwich ELISA) ELISA Kit - LS-F39994

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

31.2 - 2000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Plasma, Serum

Price:

1 Plate/$1,150

Select

Rat RSPO1 / RSPO Protein (Recombinant His, N-Terminal) (Ala136-Thr262) - LS-G16203

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

15.6 kDa

Price:

10 µg/$283; 50 µg/$452; 100 µg/$725; 200 µg/$905; 1 mg/$2,020; 500 µg/$1,558; 5 mg/$3,165; 2 mg/$2,209

Select

RSPO1 / RSPO Antibody (aa21-263, clone OTI1C3) LS-C339316

Antibody:

RSPO1 / RSPO Mouse anti-Human Monoclonal (aa21-263) (OTI1C3) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$434

Select

RSPO1 / RSPO Antibody (aa21-263, clone OTI1C3, Carrier-free) LS-C790370

Antibody:

RSPO1 / RSPO Mouse anti-Human Monoclonal (aa21-263) (Carrier-free) (OTI1C3) Antibody

Reactivity:

Human

Applications:

IHC, WB

Format:

Unconjugated, Carrier-free

Price:

100 µg/$511

• Unconjugated
• Unconjugated, Carrier-free

• Unconjugated
• Unconjugated, Carrier-free

Select

RSPO1 / RSPO Antibody (clone 7A6) LS-C108726

Antibody:

RSPO1 / RSPO Mouse anti-Human Monoclonal (7A6) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µl/$435

Select

RSPO1 / RSPO Antibody (aa206-240) LS-C393099

Antibody:

RSPO1 / RSPO Rabbit anti-Human Polyclonal (aa206-240) Antibody

Reactivity:

Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

200 µl/$393

Select

RSPO1 / RSPO Antibody LS-C489014

Antibody:

RSPO1 / RSPO Rabbit anti-Mouse Polyclonal Antibody

Reactivity:

Mouse

Applications:

ELISA

Format:

Unconjugated

Price:

100 µl/$412

Select

RSPO1 / RSPO Antibody LS-C834529

Antibody:

RSPO1 / RSPO Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

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