RRP8

ribosomal RNA processing 8, methyltransferase, homolog (yeast)

Essential component of the eNoSC (energy-dependent nucleolar silencing) complex, a complex that mediates silencing of rDNA in response to intracellular energy status and acts by recruiting histone-modifying enzymes. The eNoSC complex is able to sense the energy status of cell: upon glucose starvation, elevation of NAD+/NADP+ ratio activates SIRT1, leading to histone H3 deacetylation followed by dimethylation of H3 at 'Lys-9' (H3K9me2) by SUV39H1 and the formation of silent chromatin in the rDNA locus. In the complex, RRP8 binds to H3K9me2 and probably acts as a methyltransferase. Its substrates are however unknown.

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Products

Antibodies (23)

Proteins (4)

Type

Over-Expression Lysate (2)

Primary (23)

Recombinant (2)

Target

RRP8 (27)

Reactivity

Human (23)

Mouse (4)

Rat (4)

Application

IHC (11)

IHC-P (6)

WB (20)

ELISA (7)

IF (2)

IP (1)

Peptide-ELISA (2)

Host

rabbit (22)

mouse (1)

Product Group

IHCPlus (1)

Isotype

IgG (12)

Clonality

polyclonal pc (23)

Format

Biotin Conjugated (2)

FITC Conjugated (2)

HRP Conjugated (2)

Unconjugated (17)

Epitope

aa100-149 (4)

aa89-138 (4)

240-320 aa, Internal (1)

Internal (1)

Leu310 (1)

N-Terminus (1)

aa1-50 (1)

aa271-320 (1)

aa406-456 (1)

Publications

No (27)

Tag

GST (1)

Myc-DDK (Flag) (3)

Species

Human (3)

Source

293T Cells (1)

HEK 293 Cells (2)

Wheat Germ Extract (1)

Purification

Purified (1)

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RRP8 Antibody LS-C752958

Antibody:

RRP8 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC, WB

Format:

Unconjugated

Price:

100 µg/$341

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RRP8 Antibody (aa89-138) LS-B11561

Antibody:

RRP8 Rabbit anti-Human Polyclonal (aa89-138) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$485

Select

RRP8 Antibody (aa89-138, HRP) LS-C475899

Antibody:

RRP8 Rabbit anti-Human Polyclonal (aa89-138) (HRP) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

HRP Conjugated

Price:

100 µl/$469

Select

RRP8 Antibody (aa89-138, Biotin) LS-C475897

Antibody:

RRP8 Rabbit anti-Human Polyclonal (aa89-138) (Biotin) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Biotin Conjugated

Price:

100 µl/$469

Select

RRP8 Antibody (aa89-138, FITC) LS-C475898

Antibody:

RRP8 Rabbit anti-Human Polyclonal (aa89-138) (FITC) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

RRP8 Antibody LS-C830801

Antibody:

RRP8 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

Select

RRP8 Antibody (240-320 aa, Internal) LS-C382665

Antibody:

RRP8 Rabbit anti-Human Polyclonal (240-320 aa, Internal) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

Select

RRP8 Antibody LS-C804943

Antibody:

RRP8 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IF, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

Select

RRP8 Antibody (Leu310) LS-C177358

Antibody:

RRP8 Rabbit anti-Human Polyclonal (Leu310) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$321; 100 µl/$403

Select

RRP8 Antibody (Internal) LS-C368896

Antibody:

RRP8 Rabbit anti-Human Polyclonal (Internal) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

30 µl/$255; 100 µl/$299; 200 µl/$351

Select

RRP8 Antibody LS-C832319

Antibody:

RRP8 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

Select

RRP8 Antibody LS-C830159

Antibody:

RRP8 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

Select

RRP8 Antibody LS-C831618

Antibody:

RRP8 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

Select

RRP8 Antibody LS-C826947

Antibody:

RRP8 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$357

Select

RRP8 Antibody (aa271-320) LS-C119843

Antibody:

RRP8 Rabbit anti-Human Polyclonal (aa271-320) Antibody

Reactivity:

Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

Select

RRP8 Antibody (N-Terminus) LS-C131113

Antibody:

RRP8 Rabbit anti-Human Polyclonal (N-Terminus) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$688

Select

RRP8 Antibody (aa100-149) LS-C170504

Antibody:

RRP8 Rabbit anti-Human Polyclonal (aa100-149) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

Select

RRP8 Antibody (aa100-149, HRP) LS-C475902

Antibody:

RRP8 Rabbit anti-Human Polyclonal (aa100-149) (HRP) Antibody

Reactivity:

Human

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$469

Select

RRP8 Antibody (aa100-149, Biotin) LS-C475900

Antibody:

RRP8 Rabbit anti-Human Polyclonal (aa100-149) (Biotin) Antibody

Reactivity:

Human

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$469

Select

RRP8 Antibody (aa100-149, FITC) LS-C475901

Antibody:

RRP8 Rabbit anti-Human Polyclonal (aa100-149) (FITC) Antibody

Reactivity:

Human

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

RRP8 Antibody (aa1-50) LS-C290841

Antibody:

RRP8 Rabbit anti-Human Polyclonal (aa1-50) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

10 µl/$295; 100 µl/$514

Select

RRP8 Antibody (aa406-456) LS-C290844

Antibody:

RRP8 Rabbit anti-Human Polyclonal (aa406-456) Antibody

Reactivity:

Human

Applications:

IP

Format:

Unconjugated

Price:

10 µg/$295; 100 µl/$514

Select

RRP8 Antibody LS-C308622

Antibody:

RRP8 Mouse anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

50 µg/$705

Select

RRP8 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G113291

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

50.5 kDa

Price:

100 µg/$494

Select

Human RRP8 Protein (Recombinant GST) (Full Length) - LS-G32817

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

77.1 kDa

Price:

10 µg/$479; 25 µg/$670

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