LSBio
LSBio
Products
Services
Research Areas
Resources
Contact Us
Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

LSBio
2401 Fourth Avenue Suite 900
Seattle WA 98121

Phone: 866-819-4732 (Toll Free North America)
206-374-1102 (International)

Fax: 866-206-6909 (Toll Free North America)
206-577-4565 (International)

How to Buy - Details about how to buy our products.

Orders@LSBio.com - To submit a new order.

Customer.Support@LSBio.com - To submit questions about existing orders, pricing, availability, bulk quotes, proforma invoice requests, or other billing issues.

Technical.Support@LSBio.com - To request technical information requests about an LSBio product or its application.

Sales@LSBio.com - To request information about fee-for-service contract IHC studies, IHC reports, distribution agreements, or general business development.

Worldwide Distributors List - To find your local distributor if you're not within the United States.
Products
Services
Research Areas
Resources
Contact Us
RRM2B / P53R2 Antibody (aa128‑157) LS‑C162769
P53R2 antibody LS-C162769 is an unconjugated rabbit polyclonal antibody to human P53R2 (RRM2B). Validated for WB.
Catalog
Size
Price
LS-C162769-400
400 µl
Unavailable

Popular RRM2B / P53R2 Products

Anti-RRM2B / p53R2 antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B545 concentration 5 ug/ml.
Species: Human
Applications: IHC, IHC - Paraffin, Western blot
Anti-RRM2B antibody - Western Blot. Western blot of affinity purified anti-RRM2B antibody shows detection of recombinant (lanes 1 and 3) and endogenous protein (lanes 1 to 4) in whole cell extracts from transfected 293T. Lane 1 contains purified recombinant human p53R2. Lane 2 contains 293T cells transfected with control vector. Lane 3 contains 293T transfected with p53R2-myc. Lane 4:293T transfected with ScRNA. Lane 5:293T transfected with p53R2 SiRNA The band at 40.7 kD, indicated by the bottom arrowhead, corresponds to the expected molecular weight of endogenous RRM2B. The band with the middle arrow corresponds to myc-tagged p53R2 at 41.9kD. The highest band at 44.3 kD corresponds to recombinant p53R2. Primary antibody was diluted to 1 ug/mL and incubated overnight at 4C. ECL detection was used.
Species: Human
Applications: IHC, Immunofluorescence, Western blot, Immunoprecipitation, ELISA
WB of RRM2B antibody. Lane 1: Rat Thymus Tissue Lysate. Lane 2: MCF-7 Cell Lysate. Lane 3: A431 Cell Lysate. Lane 4: HELA Cell Lysate..
Species: Human, Monkey, Mouse, Rat, Bat, Bovine, Horse, Pig, Rabbit, Sheep, Chicken, Xenopus
Applications: Western blot
Immunohistochemistry of paraffin-embedded human tonsil using antibody at 1:100 dilution.
Species: Human
Applications: IHC, IHC - Paraffin, Western blot, ELISA
Antibody
Species: Human
Applications: IHC, IHC - Paraffin, Western blot, ELISA

Product Description

P53R2 antibody LS-C162769 is an unconjugated rabbit polyclonal antibody to human P53R2 (RRM2B). Validated for WB.
About RRM2B / P53R2
The p53 tumor-suppressor gene integrates numerous signals that control cell life and death. Several novel molecules involved in p53 signaling, including p53R2, Chk2, p53AIP1, Noxa, PIDD, and PID/MTA2, were recently discovered. p53R2 is a p53 inducible gene that contains a p53 binding sequence and encodes a subunit of the enzyme ribonucleotide reductase. p53R2 is induced by the reagents, ultraviolet and g-irradiation that cause DNA damages. Q7LG56 NM_015713 NP_056528.2

RRM2B Antibody, MTDPS8A Antibody, MTDPS8B Antibody, p53R2 Antibody, PEOA5 Antibody


Specifications

Target
Human RRM2B / P53R2
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Predicted
Monkey, Mouse (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Protein A purified
Modifications
Unmodified
Applications
  • Western blot (1:1000)
Blocking Peptide
LS-E4686 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-C162769. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Epitope
aa128-157
Specificity
This RRM2B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 128-157 amino acids from the Central region of human RRM2B.
Presentation
PBS, 0.09% sodium azide
Storage
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

Publications (0)


Customer Reviews (0)


Images


Western blot

RRM2B Antibody western blot of HepG2 cell line lysates (35 ug/lane). The RRM2B antibody detected the RRM2B protein (arrow).
RRM2B Antibody western blot of HepG2 cell line lysates (35 ug/lane). The RRM2B antibody detected the RRM2B protein (arrow).

Western blot

RRM2B Antibody western blot of HepG2 cell line lysates (35 ug/lane). The RRM2B antibody detected the RRM2B protein (arrow).
RRM2B Antibody western blot of HepG2 cell line lysates (35 ug/lane). The RRM2B antibody detected the RRM2B protein (arrow).

Western blot

RRM2B Antibody western blot of HepG2 cell line lysates (35 ug/lane). The RRM2B antibody detected the RRM2B protein (arrow).
RRM2B Antibody western blot of HepG2 cell line lysates (35 ug/lane). The RRM2B antibody detected the RRM2B protein (arrow).

Western blot

RRM2B Antibody western blot of HepG2 cell line lysates (35 ug/lane). The RRM2B antibody detected the RRM2B protein (arrow).
RRM2B Antibody western blot of HepG2 cell line lysates (35 ug/lane). The RRM2B antibody detected the RRM2B protein (arrow).


Requested From: 
Date Requested: 6/24/2018

Get Social With Us! Follow us on Facebook Follow us on Google+ Follow us on LinkedIn PSL Alliance Member
Copyright © 2018 LifeSpan BioSciences, Inc. All Rights Reserved Privacy Policy



Catalog Number