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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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RRAGC / RAGC Antibody (aa169‑198) LS‑C162764
RAGC antibody LS-C162764 is an unconjugated rabbit polyclonal antibody to human RAGC (RRAGC). Validated for IHC and WB.
Catalog
Size
Price
LS-C162764-400
400 µl
Unavailable

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Product Description

RAGC antibody LS-C162764 is an unconjugated rabbit polyclonal antibody to human RAGC (RRAGC). Validated for IHC and WB.
About RRAGC / RAGC
Guanine nucleotide-binding protein forming heterodimeric Rag complexes required for the amino acid-induced relocalization of mTORC1 to the lysosomes and its subsequent activation by the GTPase RHEB. This is a crucial step in the activation of the TOR signaling cascade by amino acids. Q9HB90 NM_022157 NP_071440.1

RRAGC Antibody, GTPase-interacting protein 2 Antibody, GTR2 Antibody, RAGC Antibody, Rag C Antibody, Rag C protein Antibody, Ras-related GTP binding C Antibody, TIB929 Antibody


Specifications

Target
Human RRAGC / RAGC
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Predicted
Mouse (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Protein A purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin (1:10 - 1:50)
  • Western blot (1:1000)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Blocking Peptide
LS-E2173 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-C162764. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Epitope
aa169-198
Specificity
This RRAGC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 169-198 amino acids from the Central region of human RRAGC.
Presentation
PBS, 0.09% sodium azide
Storage
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Immunohistochemistry

RRAGC Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human uterus tissue followed by peroxidase-conjugated secondary antibody and DAB staining.
RRAGC Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human uterus tissue followed by peroxidase-conjugated secondary antibody and DAB staining.

Western blot

RRAGC Antibody western blot of 293,MDA-MB231,HeLa,HepG2 cell line lysates (35 ug/lane). The RRAGC antibody detected the RRAGC protein (arrow).
RRAGC Antibody western blot of 293,MDA-MB231,HeLa,HepG2 cell line lysates (35 ug/lane). The RRAGC antibody detected the RRAGC protein (arrow).

Immunohistochemistry

RRAGC Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human uterus tissue followed by peroxidase-conjugated secondary antibody and DAB staining.
RRAGC Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human uterus tissue followed by peroxidase-conjugated secondary antibody and DAB staining.

Western blot

RRAGC Antibody western blot of 293,MDA-MB231,HeLa,HepG2 cell line lysates (35 ug/lane). The RRAGC antibody detected the RRAGC protein (arrow).
RRAGC Antibody western blot of 293,MDA-MB231,HeLa,HepG2 cell line lysates (35 ug/lane). The RRAGC antibody detected the RRAGC protein (arrow).

Immunohistochemistry

RRAGC Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human uterus tissue followed by peroxidase-conjugated secondary antibody and DAB staining.
RRAGC Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human uterus tissue followed by peroxidase-conjugated secondary antibody and DAB staining.

Western blot

RRAGC Antibody western blot of 293,MDA-MB231,HeLa,HepG2 cell line lysates (35 ug/lane). The RRAGC antibody detected the RRAGC protein (arrow).
RRAGC Antibody western blot of 293,MDA-MB231,HeLa,HepG2 cell line lysates (35 ug/lane). The RRAGC antibody detected the RRAGC protein (arrow).

Immunohistochemistry

RRAGC Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human uterus tissue followed by peroxidase-conjugated secondary antibody and DAB staining.
RRAGC Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human uterus tissue followed by peroxidase-conjugated secondary antibody and DAB staining.

Western blot

RRAGC Antibody western blot of 293,MDA-MB231,HeLa,HepG2 cell line lysates (35 ug/lane). The RRAGC antibody detected the RRAGC protein (arrow).
RRAGC Antibody western blot of 293,MDA-MB231,HeLa,HepG2 cell line lysates (35 ug/lane). The RRAGC antibody detected the RRAGC protein (arrow).


Requested From: 
Date Requested: 6/19/2018

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